64-31-3

Basic information

• Product Name: MORPHINE SULFATE NARCOTIC ANALGESIC
• Synonyms: MORPHINE SULFATE NARCOTIC ANALGESIC;6-alpha-diol,7,8-didehydro-4,5-alpha-epoxy-17-methyl-morphinan-sulfate;6-diol,7,8-didehydro-4,5-epoxy-17-methyl-(5alpha,6alpha)-morphinan-sulf;ate(2:1)(salt);l-morphinesulfate;MORPHINE SULFATE METHANOL SOLUTION;Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5.alpha.,6.alpha.)-, sulfate (2:1) (salt);Avinza
• CAS NO: 64-31-3
• Molecular Formula: 2C₁₇H₁₉NO₃*H₂O₄S
• Molecular Weight: 415.458
• EINECS: 200-582-8
• Mol File: 64-31-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 250 °C
• Boiling Point: 476.2°C at 760 mmHg
• Flash Point: 11℃
• Appearance: /
• Vapor Pressure: 7.06E-10mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: MORPHINE SULFATE NARCOTIC ANALGESIC(CAS DataBase Reference)
• NIST Chemistry Reference: MORPHINE SULFATE NARCOTIC ANALGESIC(64-31-3)
• EPA Substance Registry System: MORPHINE SULFATE NARCOTIC ANALGESIC(64-31-3)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: UN 1230 3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 64-31-3(Hazardous Substances Data)

Usage

Uses

Analgesic (narcotic).

Safety Profile

Poison by subcutaneous, intravenous, intraperitoneal, and intramuscular routes. Moderately toxic by ingestion and parenteral routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Used as a narcotic. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and SOx.

InChI:InChI=1/C17H19NO3.H2O4S/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;1-5(2,3)4/h2-5,10-11,13,16,19-20H,6-8H2,1H3;(H2,1,2,3,4)/t10-,11+,13-,16-,17-;/m0./s1

Upstream product

• 57-27-2 MORPHIN 

Downstream Products

• 561-27-3 Diamorphine 
• 58772-72-8 3,6-diacetylnormethylmorphine 
• 5140-28-3 3-O-acetylmorphine 
• 1422173-25-8 C₂₄H₂₂FNO₃ 
• 105092-16-8 7,8-didehydro-4,5-epoxy-17-methyl-(5α,6α)-morphinan-3,6-diol 3-benzoate 
• 466-99-9 hydromorphone 
• 948017-85-4 metamorphine 
• 519-98-2 4-methylaminoantipyrine 
• 57-27-2 MORPHIN 
• 125-29-1 Hydrocodone 

Relevant articles and documents

MORPHINE SULFATE METHANOLIC SOLVATE, PROCESSES FOR MAKING SAME AND RELATED COMPOSITIONS AND METHODS FOR TREATING PAIN

Processes for reducing the amount of impurities, especially α,β-unsaturated ketones (ABUK), in materials containing morphine. Novel compounds, namely low ABUK morphine sulfate methanolic solvate, and a novel crystal form are also described. The method for making morphine sulfate methanolic solvate comprises mixing a morphine free base composition with methanol to form a solution and adding a liquid comprising sulfuric acid to the solution to form a morphine sulfate methanolic solvate precipitate. A method of making a morphine sulfate compound comprises drying the morphine sulfate methanolic solvate in the presence of water vapor, such that methanol molecules are removed and replaced with water vapor molecules. A composition for treating pain comprises the morphine sulfate compound and at least one pharmaceutically acceptable excipient. A method for treating pain comprises administering to a patient in need thereof the composition comprising the morphine sulfate compound and at least one pharmaceutically acceptable excipient.