640291-96-9

Usage

Uses

Used in Pharmaceutical Industry:
(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL is used as a building block for the synthesis of pharmaceuticals due to its unique chemical and biological properties. It serves as a versatile intermediate for creating novel compounds with potential therapeutic applications.
Used in Agrochemical Industry:
(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL is used as a building block for the synthesis of agrochemicals, contributing to the development of new compounds with agricultural applications, such as pesticides or herbicides.
Used in Medicinal Chemistry:
(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL is used as a versatile intermediate and scaffold in medicinal chemistry for designing novel compounds with desired biological activities, potentially leading to the discovery of new drugs and therapeutic agents.
Used in Drug Discovery:
(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL is used in drug discovery processes as a key component in the development of new pharmaceuticals, thanks to its unique properties and reactivity, which allow for the creation of diverse and effective compounds.

Upstream product

• 99-90-1 para-bromoacetophenone 
• 40155-54-2 ethyl 4-(4-bromophenyl)-2,4-dioxobutanoate 
• 33277-15-5 ethyl 5-(4-bromo-phenyl)-isoxazole-3-carboxylate 

Downstream Products

• 640292-04-2 5-(4-bromo-phenyl)-isoxazole-3-carbaldehyde 
• 1056456-31-5 5-(4-bromophenyl)-3-(methoxymethyl)isoxazole 
• 1188165-03-8 5-(4-bromophenyl)-3-(chloromethyl)isoxazole 
• 1378938-17-0 2-amino-3-cyano-7-dimethylamino-4-(5-(4-bromophenyl)-isoxazol-3-yl)-4H-chromene 

Relevant academic research and scientific papers

2-Amino-3-cyano-4-(5-arylisoxazol-3-yl)-4H-chromenes: Synthesis and in vitro cytotoxic activity

A new series of 4-aryl-4H-chromenes bearing a 5-arylisoxazol-3-yl moiety at the C-4 position were prepared as potential anticancer agents. The in vitro cytotoxic activity of the synthesized compounds was investigated against a panel of tumor cell lines in

NOVEL PHENYLPROPIONIC ACID DERIVATIVES AS PEROXISOME PROLIFERATOR-ACTIVATED GAMMA RECEPTOR MODULATORS, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention provides a novel phenylpropionic acid derivative and a PPAR-γ modulator comprising the same as an active ingredient. The phenylpropionic acid derivative of the present invention has modulatory action on function of PPAR-γ and then exhibits hypoglycemic, hypolipidemic and insulin resistance-reducing effects on PPAR-mediated diseases or disorders. Therefore, the present invention is prophylactically or therapeutically effective for diabetes and metabolic diseases.

NOVEL PHENYLPROPIONIC ACID DERIVATIVES AS PEROXISOME PROLIFERATOR-ACTIVATED GAMMA RECEPTOR MODULATORS, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention provides a novel phenylpropionic acid derivative and a PPAR-γ modulator comprising the same as an active ingredient. The phenylpropionic acid derivative of the present invention has modulatory action on function of PPAR-γ and then exhibits hypoglycemic, hypolipidemic and insulin resistance-reducing effects on PPAR-mediated diseases or disorders. Therefore, the present invention is prophylactically or therapeutically effective for diabetes and metabolic diseases.

Facile Baylis-Hillman Reaction of Substituted 3-Isoxazolecarbaldehydes: The Impact of a Proximal Heteroatom Within a Heterocycle on the Acceleration of the Reaction

The fast and facile Baylis-Hillman reaction in substituted 3-isoxazolecarbaldehydes confirms the impact of the proximal heteroatom within a heterocycle towards enhanced reactivity of the formyl group for this reaction.