64055-59-0Relevant academic research and scientific papers
Copper-catalyzed domino synthesis of quinazolinones via Ullmann-type coupling and aerobic oxidative C-H amidation
Xu, Wei,Jin, Yibao,Liu, Hongxia,Jiang, Yuyang,Fu, And Hua
, p. 1274 - 1277 (2011)
An efficient copper-catalyzed approach to quinazolinone derivatives has been developed, and the protocol uses cheap and readily available substituted 2-halobenzamides and (aryl)methanamines as the starting materials as well as economical and environmentally friendly air as the oxidant. This can be the first example of constructing N-heterocycles via sequential Ullmann-type coupling under air and aerobic oxidative C-H amidation.
