64068-76-4Relevant academic research and scientific papers
1-phenyl-2-phenylaminoethyl ketone derivative and medical application
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Paragraph 0137; 0138, (2020/04/17)
The invention belongs to the field of pharmaceutical chemicals, and relates to a micromolecular inhibitor of polymyxin drug-resistant protein MCR-1 and application thereof. The invention relates to acompound shown as a formula I, a pharmaceutically accept
Design, synthesis and biological evaluation of 1-Phenyl-2-(phenylamino) Ethanone Derivatives as Novel MCR-1 Inhibitors
Lan, Xiu-juan,Yan, Hai-tao,Lin, Feng,Hou, Shi,Li, Chen-chen,Wang, Guang-shu,Sun, Wei,Xiao, Jun-hai,Li, Song
supporting information, (2019/08/07)
Polymyxins are considered to be the last-line antibiotics that are used to treat infections caused by multidrug-resistant (MDR) gram-negative bacteria; however, the plasmid-mediated transferable colistin resistance gene (mcr-1) has rendered polymyxins ine
INTERMEDIATES AND PROCESS FOR THE PREPARATION OF HIGH PURITY FINGOLIMOD HYDROCHLORIDE
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Page/Page column 21; 22, (2014/08/06)
The present invention relates to a simple and commercially feasible preparation of Fingolimod hydrochloride with high purity of greater than 99.9%. The.present invention also provides novel intermediates for the preparation of Fingolimod Hydrochloride of Formula 1.
Production of 2-amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diols
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, (2008/06/13)
Disclosed is a process for the production of 2-amino-2-[2-(4-C2-20-alkyl-phenyl)ethyl]propane-1,3-diols.
A new efficient synthesis of the immunosuppressive agent FTY-720
Durand, Philippe,Peralba, Philippe,Sierra, Frederique,Renaut, Patrice
, p. 505 - 506 (2007/10/03)
A new efficient five-step synthesis of the immunosuppressive agent FTY- 720 is described.
Transitions de Phase en Series Mesogenes: Les di TTF et les diTTF
Chann, N. B.,Cotrait, M.,Gautlier, J.,Haget, Y.,Tinh, Nguyen Huu,et al.
, p. 129 - 142 (2007/10/02)
The polymorphism of the di(4-alkylphenyl) and di(4-alkoxyphenyl) tetrathiafulvalene (TTF) is investigated by optical, crystallographic and calorimetric methods.All the studied derivatives are mesomorphic.The first mesophase is always a smectic G phase; th
MESOMORPHIC TRANSITION METAL COMPLEXES.
Giroud,Mueller-Westerhoff
, p. 11 - 13 (2007/10/12)
The synthesis of two dithiolato nickel complexes carrying aliphatic substituents is described. Both compounds exhibit mesomorphic properties.
