640721-01-3Relevant articles and documents
Coumarin-4-ylmethoxycarbonyls as Phototriggers for Alcohols and Phenols
Suzuki, Akinobu Z.,Watanabe, Takayoshi,Kawamoto, Mika,Nishiyama, Keiko,Yamashita, Hirotaka,Ishii, Megumi,Iwamura, Michiko,Furuta, Toshiaki
, p. 4867 - 4870 (2007/10/03)
(Equation Presented) Caged compounds can be used to regulate the spatial and temporal dynamics of signaling molecules in live cells. Photochemical properties of coumarin-4-ylmethoxy carbonates (1a-d) are investigated to construct caged compounds of hydroxy-containing molecules. All the compounds possess desired properties as phototriggers for alcohols and phenols. The 6-bromo-7-hydroxycoumarin-4-ylmethoxycarbonyl (Bhcmoc) group has the highest photochemical efficiency and is applied to make caged compounds of 1,2-dioctanoylglycerol (diC8), Tyr-OMe, and adenosine.