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Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 42205-33-4 ethyl 3-(4-bromophenyl)-2-cyanoacrylate 
• 79-04-9 chloroacetyl chloride 
• 158833-80-8 ethyl 2-amino-4-(4-bromophenyl)-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carboxylate 

Relevant academic research and scientific papers

Synthesis and biological evaluation of some new coumarin derivatives

Pyrimidino[5′,4′-6,5]-,pyridino[3′,2′-6,5]- and pyrrolo[3′,2′-5,6]4H-pyrano-[3,2-c][1]benzopyran-6-one derivatives (5-7 and 10) could be obtained via reaction of 2-amino-4-(p-bromophenyl)-3- cyano(carboethoxy)-4H,5H-pyrano[3,2-c][1]benzopyran-5-ones (3a,b) with a variety of reagents. Alkylation of (3b) with either 2-furoyl chloride or chloroacetyl chloride gave the 2-N-substituted derivatives (9a,b). Benzofurano[3,2-b]4H-pyran derivative (12) was also prepared. The antimicrobial activity of the prepared compounds was tested.