1741-50-0

Basic information

• Product Name: 5-Bromo-2-phenylbenzimidazole
• Synonyms: 1H-BenziMidazole, 6-broMo-2-phenyl-1H-BenziMidazole, 5-broMo-2-phenyl- (9CI);5-BROMO-ALPHA-PHENYL BENZIMIDAZOLE;5-bromo-2-phenylbenzimidazole;5-BROMO-A-PHENYL BENZIMIDAZOLE;5-BRONO-A-PHENYLBENZIMIDAZOLE;5-BroMo-2-phenyl-1H-benzo[d]iMidazole
• CAS NO: 1741-50-0
• Molecular Formula: C₁₃H₉BrN₂
• Molecular Weight: 273.13
• Mol File: 1741-50-0.mol
• Article Data: 45

Chemical Properties

• Boiling Point: 446.2 °C at 760 mmHg
• Flash Point: 223.6 °C
• Appearance: /
• Density: 1.546 g/cm³
• Vapor Pressure: 3.72E-08mmHg at 25°C
• Refractive Index: 1.708
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-Bromo-2-phenylbenzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-phenylbenzimidazole(1741-50-0)
• EPA Substance Registry System: 5-Bromo-2-phenylbenzimidazole(1741-50-0)

Safety Data

• Hazardous Substances Data: 1741-50-0(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-phenylbenzimidazole is a chemical compound with the molecular formula C13H9BrN2. It is an organic compound that is derived from benzimidazole and contains a bromine atom and a phenyl group. 5-Bromo-2-phenylbenzimidazole is used in the pharmaceutical industry for its potential biological activities, such as anticancer, antiviral, and antifungal properties. It has also been studied for its potential use in organic light-emitting diodes (OLEDs) and as a fluorescence probe for nucleic acids. 5-Bromo-2-phenylbenzimidazole is a versatile chemical with potential applications in various fields due to its unique structural and chemical properties.

InChI:InChI=1/C13H9BrN2/c14-10-6-7-11-12(8-10)16-13(15-11)9-4-2-1-3-5-9/h1-8H,(H,15,16)

Upstream product

• 21719-91-5 N′-(4-bromophenyl)benzamidine 
• 1242182-79-1 N-(3-bromophenyl)benzamidine 
• 100-47-0 benzonitrile 
• 591-19-5 m-Bromoaniline 
• 100-46-9 benzylamine 
• 1575-37-7 4-Bromo-benzene-1,2-diamine 
• 611-73-4 Benzoylformic acid 
• 100-51-6 benzyl alcohol 
• 64085-52-5 5-bromo-2-iodo-aniline 
• 66416-72-6 4-bromo-2-iodoaniline 
• 1418298-88-0 C₁₃H₁₀BrIN₂ 
• 106-40-1 4-bromo-aniline 
• 875-51-4 4-Bromo-2-nitroaniline 
• 707-07-3 orthobenzoic acid trimethyl ester 

Downstream Products

• 1257250-52-4 2-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole 
• 1463056-15-6 4-amino-8-(2-phenyl-1H-benzo[d]imidazol-6-yl)cinnoline-3-carboxamide 
• 1257250-52-4 2-phenyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole 
• 1613695-61-6 C₁₈H₁₅N₃O 

Relevant articles and documents

One-Pot Transformation of Lignin and Lignin Model Compounds into Benzimidazoles

It is a challenging task to simultaneously achieve selective depolymerization and valorization of lignin due to their complex structure and relatively stable bonds. We herein report an efficient depolymerization strategy that employs 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as oxidant/catalyst to selectively convert different oxidized lignin models to a wide variety of 2-phenylbenzimidazole-based compounds in up to 94 % yields, by reacting with o-phenylenediamines with varied substituents. This method could take full advantage of both Cβ and/or Cγ atom in lignin structure to furnish the desirable products instead of forming byproducts, thus exhibiting high atom economy. Furthermore, this strategy can effectively transform both the oxidized hardwood (birch) and softwood (pine) lignin into the corresponding degradation products in up to 45 wt% and 30 wt%, respectively. Through a “one-pot” process, we have successfully realized the oxidation/depolymerization/valorization of natural birch lignin at the same time and produced the benzimidazole derivatives in up to 67 wt% total yields.

One-pot Synthesis of Benzimidazoles Using H2SO4@HTC as Catalyst

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A heterogeneous catalytic strategy for facile production of benzimidazoles and quinoxalines from primary amines using the Al-MCM-41 catalyst

This study reports a straightforward heterogeneous catalytic (Al-MCM-41) approach to synthesize nitrogen heterocycle moieties from primary amines under solvent-free conditions. The Al-MCM-41 catalyst was prepared using a hydrothermal method and characterized by various analytical techniques. The probability and limitations of the catalytic methodology were presented with various substrates. The catalytic method grants an attractive route to a wide variety of benzimidazole and quinoxaline moieties with good to excellent yields. The gram scale reaction and reusability (up to five cycles) of the Al-MCM-41 catalyst would greatly benefit industrial applications. This journal is