64088-74-0Relevant articles and documents
Inhibition of murine thymidylate synthase and human dihydrofolate reductase by 5,8-dideaza analogues of folic acid and aminopterin
Hynes,Patil,Tomazic,Kumar,Pathak,Tan,Xianqiang,Ratnam,Delcamp,Freisheim
, p. 449 - 454 (2007/10/02)
A series of 5,8-dideaza analogues of folic acid, isofolic acid, aminopterin, and isoaminopterin were evaluated for inhibition of thymidylate synthase, TS, from mouse L1210 leukemia cells with 10-propargyl-5,8-dideazafolic acid, CB3717, 4a, as the referenc