64172-98-1

Usage

Uses

Used in Pharmaceutical Synthesis:
N-4-CBZ-2-PIPERAZINECARBOXYLIC ACID is used as a precursor in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structures of different drugs, enhancing their therapeutic properties and effectiveness.
Used in Organic Chemistry:
In the field of organic chemistry, N-4-CBZ-2-PIPERAZINECARBOXYLIC ACID is used as a building block for constructing more complex molecules, facilitating the development of novel chemical entities with potential applications in various industries.
Used in Drug Development:
N-4-CBZ-2-PIPERAZINECARBOXYLIC ACID is utilized in drug development for its potential biological activities, including antifungal and anticonvulsant properties, which are being explored for the creation of new therapeutic agents to address various health conditions.
Used in Chemical Research:
In chemical research, N-4-CBZ-2-PIPERAZINECARBOXYLIC ACID is employed to study its properties and reactivity, contributing to the advancement of knowledge in organic chemistry and potentially leading to the discovery of new applications and uses for N-4-CBZ-2-PIPERAZINECARBOXYLIC ACID.

Upstream product

• 2762-32-5 piperazine-2-carboxylic acid 
• 1885-14-9 phenyl chloroformate 
• 1214196-85-6 1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid 
• 501-53-1 benzyl chloroformate 
• 149057-19-2 4-((benzyloxy)carbonyl)-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid 
• 3022-15-9 piperazine-2-carboxylic acid dihydrochloride 
• 7758-99-8 copper(II) sulfate 

Downstream Products

• 276695-15-9 4-Carbobenzyloxy-1-(5,6-Dichloro-2-Nitrophenyl)-Piperazine-2-Carboxylic Acid 
• 304023-12-9 4-(2-chloro-6-nitro-phenyl)-piperazine-1,3-dicarboxylic acid 1-benzyl ester 
• 276695-07-9 4-carbobenzyloxy-1-(4,5-dichloro-2-nitrophenyl)piperazine-2-carboxylic acid 
• 276695-19-3 4-carbobenzyloxy-1-(4,5-difluoro-2-nitrophenyl)-piperazine-2-carboxylic acid 
• 304023-21-0 4-(3,5-dichloro-2-nitro-phenyl)-piperazine-1,3-dicarboxylic acid 1-benzyl ester 
• 276695-31-9 4-(5-chloro-2-nitro-4-trifluoromethyl-phenyl)-piperazine-1,3-dicarboxylic acid 1-benzyl ester 
• 64182-68-9 4-carbobenzoxy-1-(5-chloro-2-nitrophenyl)piperazine-2-carboxylic acid 
• 304023-14-1 4-(5-fluoro-2-nitro-phenyl)-piperazine-1,3-dicarboxylic acid 1-benzyl ester 
• 304023-13-0 4-(5-hydroxy-2-nitro-phenyl)-piperazine-1,3-dicarboxylic acid 1-benzyl ester 
• 64182-55-4 4-carbobenzoxy-1-(5-methoxy-2-nitrophenyl)piperazine-2-carboxylic acid 
• 64182-77-0 4-carbobenzoxy-1-(5-methyl-2-nitrophenyl)piperazine-2-carboxylic acid 
• 304023-17-4 4-(4-amino-2-nitro-phenyl)-piperazine-1,3-dicarboxylic acid 1-benzyl ester 
• 64182-58-7 4-carbobenzyloxy-l-(4-chloro-2-nitrophenyl)piperazine-2-carboxylic acid 
• 304023-16-3 4-(4-carbamoyl-2-nitro-phenyl)-piperazine-1,3-dicarboxylic acid 1-benzyl ester 

Relevant academic research and scientific papers

HEPATITIS B CAPSID ASSEMBLY MODULATORS

Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.

SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS

There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin and/or kallikrein, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which diseases or disorders are amenable to treatment or prevention by the inhibition of thrombin and/or kallikrein.

NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE

The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

DIKETO AZOLOPIPERIDINES AND AZOLOPIPERAZINES AS ANTI-HIV AGENTS

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, diketo fused azolopiperidine and azolopiperazine derivatives that possess unique antiviral activity are provided. These compounds are useful the treatment of HIV and AIDS.

Substituted pyrazinoquinoxaline derivatives as serotonin receptor agonist and antagonists ligands

The present invention is directed to novel compounds represented by structural Formulas (I) and (I-a): or a pharmaceutically acceptable salt thereof, wherein R1, R4a, R4b, R5, R6, R7, R8, R9, n, and X are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep and sexual disorders, migraine and other conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.

2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)one derivatives

This invention provides compounds of formula I, wherein R is hydrogen or alkyl of 1-6 carbon atoms; R′ is hydrogen, alkyl of 1-6 carbon atoms, acyl of 2-7 carbon atoms, or aroyl; R1, R2, R3, and R4are each, inde

2,3,4,4a-tetrahydro-1H-pyrazino-[1,2a] quinoxalin-5- (6H) one derivatives

This invention provides compounds of formula I, wherein R is hydrogen or alkyl of 1-6 carbon atoms; R′ is hydrogen, alkyl of 1-6 carbon atoms, acyl of 2-7 carbon atoms, or aroyl; R1, R2, R3, and R4 are each, ind

2,3,4,4A-Tetrahydro-1H-pyrazino[1,2-a,]quinoxalin-5(6H)-ones and derivatives thereof for relieving hypertension

Compounds of the formula STR1 wherein R is hydrogen (lower)alkyl, phen(lower)alkyl, benzoyl(lower)alkyl, or p-halobenzoyl(lower)alkyl; R1 is hydrogen or (lower)alkyl; R2 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, trifluoromethyl, or amino in the 7-, 8-, or 9-position; R3 is hydrogen, or (lower)alkyl; and R4 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, or trifluoromethyl in the 7-, 8-, or 9-position; or the non-toxic acid addition salts thereof; exert a hypotensive effect in hypertensive animals.