64180-67-2

Usage

Uses

Used in Pharmaceutical Industry:
(1R,4E,6S,7R,10E,14R)-6-Hydroxy-10,14-dimethyl-7-(1-methylethenyl)-15-oxabicyclo[12.1.0]pentadeca-4,10-diene-4-methanol could be used as a pharmaceutical compound for its potential biological activity. Its complex structure and functional groups may allow it to interact with biological targets, making it a candidate for drug development.
Used in Chemical Research:
In the field of chemical research, (1R,4E,6S,7R,10E,14R)-6-Hydroxy-10,14-dimethyl-7-(1-methylethenyl)-15-oxabicyclo[12.1.0]pentadeca-4,10-diene-4-methanol could be used as a subject for studying the synthesis and reactions of complex organic molecules. Its unique structure may provide insights into new chemical pathways and mechanisms.
Used in Material Science:
(1R,4E,6S,7R,10E,14R)-6-Hydroxy-10,14-dimethyl-7-(1-methylethenyl)-15-oxabicyclo[12.1.0]pentadeca-4,10-diene-4-methanol may have potential applications in material science, where its structural properties could be harnessed to develop new materials with specific characteristics.

InChI:InChI=1/C20H32O3/c1-14(2)17-9-7-15(3)6-5-11-20(4)19(23-20)10-8-16(13-21)12-18(17)22/h6,12,17-19,21-22H,1,5,7-11,13H2,2-4H3/b15-6+,16-12+

Upstream product

• 104322-56-7 [(4E,10E)-(1R,6S,7R,14R)-6-(2-Ethoxy-ethoxy)-7-isopropenyl-10,14-dimethyl-15-oxa-bicyclo[12.1.0]pentadeca-4,10-dien-4-yl]-methanol 
• 104322-51-2 tert-Butyl-{(E)-(2R,3R)-2-(2-ethoxy-ethoxy)-9-[(2R,3R)-3-(2-iodo-ethyl)-2-methyl-oxiranyl]-3-isopropenyl-6-methyl-non-6-enyloxy}-dimethyl-silane 
• 198494-48-3 asperdiol acetate 
• 87829-33-2 (4E,10E)-(1S,6R,7S,14S)-4-Benzyloxymethoxymethyl-7-isopropenyl-10,14-dimethyl-15-oxa-bicyclo[12.1.0]pentadeca-4,10-dien-6-ol 
• 107099-14-9 Benzoic acid (E)-(2S,5S,7S,12R,13S)-2-bromo-13-isopropenyl-1,5-dimethyl-6,16-dioxa-tricyclo[10.3.1.0^5,7]hexadec-10-en-10-ylmethyl ester 
• 87841-47-2 (2E,6E)-2,6-Dimethyl-8-phenylselanyl-octa-2,6-dien-1-ol 
• 86838-70-2 Methanesulfonic acid (5E,9E)-(1R,13S,14S)-14-hydroxy-13-isopropenyl-6,10-dimethyl-2-methylene-cyclotetradeca-5,9-dienyl ester 
• 107171-91-5 (6E,10E)-(1S,2R,3R)-3-Isopropenyl-6,10-dimethyl-14-methylene-cyclotetradeca-6,10-diene-1,2-diol 
• 59664-63-0 Mayol 
• 86853-12-5 (6E,10E)-(1S,2S,3S,14S)-3-Isopropenyl-6,10,14-trimethyl-15-oxa-bicyclo[12.1.0]pentadeca-6,10-dien-2-ol 
• 86838-67-7 (6E,10E)-(1S,2R,3S,14S)-3-Isopropenyl-6,10,14-trimethyl-15-oxa-bicyclo[12.1.0]pentadeca-6,10-dien-2-ol 
• 86848-71-7 Methanesulfonic acid (5E,9E)-(1R,13S,14S)-13-isopropenyl-6,10-dimethyl-2-methylene-14-trimethylsilanyloxy-cyclotetradeca-5,9-dienyl ester 
• 86838-72-4 rel-(1R,2S)-(3E,7E,11E)-1-isopropenyl-4-<(benzoyloxy)methyl>-8,12-dimethyl-3,7,11-cyclotetradecatrien-2-ol 
• 107099-13-8 Benzoic acid (2E,6E)-(1S,10R,14R)-10-bromo-14-isopropenyl-7,11-dimethyl-15-oxa-bicyclo[9.3.1]pentadeca-2,6-dien-3-ylmethyl ester 

Relevant academic research and scientific papers

Synthesis of cembranoid analogues and evaluation of their potential as quorum sensing inhibitors

Natural cembranoids have shown Quorum Sensing Inhibitory (QSI) activity, but their structure-function interactions are not well understood. Thirty-four cembranoid analogues were synthesized using six natural cembranoids (1-6) previously isolated from the Colombian Caribbean octocorals Eunicea knighti and Pseudoplexaura flagellosa as lead compounds. The analogues (7-40) obtained through the selected chemical transformations were tested in vitro against the QS systems of a Chromobacterium violaceum biosensor. Half of the cembranoid analogues assayed showed superior QSI activity to the lead compounds; three (8, 13, and 18) displayed remarkable potency up to three times higher than the natural compounds. Thereby, we have synthesized a pool of cembranoid QS inhibitors that can be used in concert with natural compounds to develop antipathogenic drugs and antifouling agents.