64196-54-9Relevant academic research and scientific papers
Chiral Frustrated Lewis Pairs Catalyzed Highly Enantioselective Hydrosilylations of 1,2-Dicarbonyl Compounds
Ren, Xiaoyu,Du, Haifeng
supporting information, p. 810 - 813 (2016/02/09)
A highly enantioselective hydrosilylation of 1,2-dicarbonyl compounds was successfully realized for the first time utilizing the combination of tricyclohexylphosphine and chiral alkenylborane derived in situ from diyne as a frustrated Lewis pair catalyst. A variety of optically active α-hydroxy ketones and esters were obtained in 52-98% yields with 86-99% ee's.
Reactions of aroyl chlorides with samarium metal in DMF-controllable syntheses of O-aroylbenzoins, 1,2-diarylethanones, and (z)-α, α′-stilbenediol dibenzoates
Liu, Yongjun,Wang, Xiaoxia,Zhang, Yongmin
, p. 4009 - 4022 (2007/10/03)
Reduction of aroyl chlorides carried out in DMF with samarium metal has been studied. Samarium metal, which requires not any intended activation or pretreatment, was found to react with aroyl chloride in a controllable manner. Correspondingly, O-aroylbenzoins, 1,2-diarylethanones, or (Z)-α, α′-stilbenediol dibenzoates were afforded as the major products under controlled conditions.
REDUCTIVE COUPLING OF BENZOIC ACID HALIDES AND ESTERS USING LOW-VALENT TITANIUM
Dang, Y.,Geise, H. J.
, p. 375 - 380 (2007/10/02)
The reductive coupling of (substituted) benzoic acid chlorides and esters is achieved using low-valent titanium, generated from TiCl3 and LiAlH4.Both acid chlorides and esters seem to follow the same two reaction pathways: one path via tolanes to stilbenes, the other via benzils to complex mixtures of products arising from reduction and further coupling reactions.Although the exact product balance depends upon the reaction conditions the major product is (substituted) cis-stilbene.
Preparation and Some Reactions of 3,5:8,10-Di-1,3-benzo(3,4)-1,2,5-thiadiazolocyclophane
Hatta, Taizo,Mataka, Shuntaro,Tashiro, Masashi,Suzuki, Hiroshi,Numano, Katsutoshi
, p. 289 - 293 (2007/10/02)
Titled 1,2,5-thiadiazolometacyclophane 1 was prepared via thiacyclophane 5 which was obtained by the reaction of di(bromomethyl) 2 with sodium sulfide under phase-transfer-catalyzed conditions.Cyclophane 1 gave the corresponding pyrene derivatives by the oxidative transannular reaction in the reaction with brominating reagent.Reduction of 1 with lithium aluminum hydride followed by acetylation with acetic anhydride gave a 4:1 mixture of cis- and trans-diamide 11 and 12 with a trace amount of cyclophane-ring-cleaved product 13.On the other hand, 13 was obtained as a major product in the reduction with metal sodium and diisobutyl aluminum hydride.
IODOTRIMETHYLSILANE REDUCTION OF BENZOINS: SYNTHESIS OF DEOXYBENZOINS AND TETRAARYLFURANS
Krepski, Larry R.,Heilmann, Steven M.,Rasmussen, Jerald K.,Tumey, Michael L.,Smith, Howell K.
, p. 377 - 386 (2007/10/02)
Benzoins react readily with idotriethylsilane to produce, in many cases, mixtures of deoxybenzoins and tetraarylfurans.
Reaction of Aryl Aldehydes with Thiocyanates in the Presence of Tributylphosphine
Yokoyama, Masataka,Ohteki, Hiroko,Kurauchi, Masahiko,Hoshi, Kazuko,Yanagisawa, Eizaburo,et al.
, p. 2635 - 2640 (2007/10/02)
Aryl aldehydes react with methyl thiocyanate in the presence of tributylphosphine to afford S-methyl thiobenzoates and arylacetonitriles in good yields.This is a novel disproportionation reaction involving carbon-carbon bond formation.These compounds thus obtained are easily converted into deoxybenzoins using sodium hydride.On the other hand, p-dialkylaminobenzaldehydes react with methyl thiocyanate under the same conditions to furnish both the corresponding trans-dicyanostilbenes and succinonitriles in moderate yields.Finally, the reaction was carried out with aryl thiocyanates resulting in the formation of addition products.
New Helical Molecules, IX. Syntheses, Enantiomer Separations, Circular Dichroism, Racemization Barriers, X-Ray Analyses, and Absolute Conformations of New, Easily Available Arenicenes
Voegtle, Fritz,Palmer, Michael,Fritz, Edmund,Lehmann, Ulrich,Meurer, Kurt,et al.
, p. 3112 - 3124 (2007/10/02)
The new helical compounds 1 - 3 have been synthesized. 1 and 2 are separated into the enantiomers by chromatography on cellulose triacetate.The rotatory powers are high: e.g., 20436 = 2096 for 1.The racemization /ring inversion ba
