64198-19-2Relevant academic research and scientific papers
A New Coupling Reaction of Alkyl Iodides with Electron Deficient Alkenes Nickel Boride (cat.) - Borohydride Exchange Resin in Methanol
Sim, Tae Bo,Choi, Jaesung,Joung, Meyoung Ju,Yoon, Nung Min
, p. 2357 - 2361 (2007/10/03)
The radical addition reaction of alkyl iodides with α,β-unsaturated esters, nitriles, and ketones proceeds in moderate to excellent yields (50-95%) using Ni(OAc)2 (0.05-0.2 equiv) - BER (3-5 equiv) in methanol in 1-9 h at room temperature or at 65°C. Nickel boride on borohydride exchange resin (BER) is a good alternative reagent to tributyltin hydride for the coupling of alkyl iodides with the electron deficient alkenes in methanol. Compared with tributyltin hydride method, this method has an advantage of simple workup, since nickel boride - BER can be removed readily by filtration.
13C Chemical Shift Non-Equivalence in Methylene Carbons of Monosubstituted Cyclohexanes
Ito, Hiroshi,Renaldo, Alfred F.,Johnson, Robert D.,Ueda, Mitsuru
, p. 273 - 276 (2007/10/02)
Monosubstituted cyclohexanes were synthesized by addition of a cyclohexyl radical to olefins bearing different substituents at the α-position.Six distinct methylene 13C resonances were observed, indicating that the methylene carbons located at the 2 and 6 positions and at 3 and 5 positions are not magnetically equivalent.This magnetic non-equivalence (anisochronism) observed in the monosubstituted cyclohexanes is due to the introduction of an asymmetric center β to the prochiral C-1 ring carbon atom. KEY WORDS Anisochronism Magnetic non-equivalence Cyclohexyl adducts Mercury method
Polar Substituent Effects in Additions of Alkyl Radicals to Alkenes
Giese, Bernd,Meixner, Juergen
, p. 2138 - 2145 (2007/10/02)
Reduction of cyclohexylmercuric salts (7) with NaBH4 yields cyclohexyl radicals (8).Their rel. rates of addition to substituted styrenes 4, acrylic esters 5 and acrylonitriles 6 have been measured.Comparison with Hammett ?-values shows, that substituents at the non attacked vinylic carbon atom show polar effects mainly (Table 1).The effect of a substituent variation increases with increase of the reactivity of the alkenes (Table 2).Mesomeric and steric effects play only a minor role.
HOCHDRUCK-HOCHTEMPERATUR-REAKTIONEN IN EINEM STROEMUNGSREAKTOR-VI. THERMISCHE ADDITION VON ALKANEN AN ALKENE
Metzger, Juergen,Hartmanns, Joerg,Koell, Peter
, p. 1891 - 1894 (2007/10/02)
The thermal Anti-Markownikow-addition of alkanes to activated and desactivated alkenes ("direkte substituierende Addition", "Ane-reaction") at 650-723 K and reaction times of 1-10 min. is described.
