642006-22-2

Basic information

• Product Name: 2-amino-5-methyl-4,6-diphenylnicotinonitrile
• Synonyms: 2-amino-5-methyl-4,6-diphenylnicotinonitrile
• CAS NO: 642006-22-2
• Molecular Weight: 285.348
• Mol File: 642006-22-2.mol

Chemical Properties

• CAS DataBase Reference: 2-amino-5-methyl-4,6-diphenylnicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-methyl-4,6-diphenylnicotinonitrile(642006-22-2)
• EPA Substance Registry System: 2-amino-5-methyl-4,6-diphenylnicotinonitrile(642006-22-2)

Safety Data

• Hazardous Substances Data: 642006-22-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 93-55-0 1-phenyl-propan-1-one 
• 109-77-3 malononitrile 
• 10432-39-0 2-(1-phenylpropylidene)malononitrile 
• 1421782-97-9 C₁₉H₁₄N₂ 

Relevant articles and documents

Synthesis of a novel acidic ionic liquid catalyst and its application for preparation of pyridines via a cooperative vinylogous anomeric-based oxidation

Abstract: In the current study, a novel acidic ionic liquid catalyst based on 8-hydroxyquinoline, namely 8,8′,8″-([1,3,5-triazine-2,4,6-triyl]tris[oxy])tris(1-sulfoquinolin-1-ium)chloride (TTS), was designed and synthesized. The structure of the prepared acidic ionic liquid (AIL) was fully investigated by using Fourier transform infrared (FT-IR) spectroscopy, energy dispersive X-ray (EDX) analysis, thermogravimetric analysis/differential thermal analysis (TGA/DTA), 1HNMR, 13CNMR and mass spectroscopy. Then, the catalytic performance of described AIL was successfully inspected toward the four-component synthesis of pyridine derivatives via a cooperative vinylogous anomeric-based oxidation. Graphic abstract: Novel AIL (TTS) showed a very high efficiency in the synthesis of pyridines. [Figure not available: see fulltext.].

[5C + 1N] Annulation of 2,4-pentadienenitriles with hydroxylamine: A synthetic route to multi-substituted 2-aminopyridines

A facile and efficient synthetic route to multi-substituted 2-aminopyridines has been developed via a formal [5C + 1N] annulation of readily available 2,4-pentadienenitriles with hydroxylamine (NH2OH) under very mild conditions, which involves