64241-77-6

Usage

Uses

Used in Pharmaceutical Industry:
3-Fluoro-2,2-dimethyl-propionic acid is used as an intermediate in the production of pharmaceuticals for its ability to contribute to the synthesis of active pharmaceutical ingredients. Its unique chemical structure allows it to be a key component in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Fluoro-2,2-dimethyl-propionic acid is utilized as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used in Organic Synthesis:
3-Fluoro-2,2-dimethyl-propionic acid is used as a building block in organic synthesis for its potential to form a variety of organic compounds. Its reactivity and functional groups make it a valuable precursor in the creation of specialty chemicals, fine chemicals, and other complex organic molecules for diverse applications.
Safety and Handling:
Given its classification as a hazardous substance, 3-Fluoro-2,2-dimethyl-propionic acid requires careful handling and storage to prevent exposure and environmental contamination. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, are essential when working with FDMPA.

InChI:InChI=1/C5H9FO2/c1-5(2,3-6)4(7)8/h3H2,1-2H3,(H,7,8)

Upstream product

• 1068560-15-5 methyl 3-fluoro-2,2-dimethylpropanoate 
• 14002-80-3 Methyl 2,2-dimethyl-3-hydroxypropionate 
• 17701-61-0 benzyl 2,2-dimethyl-3-hydroxypropanoic acid 
• 4835-90-9 3-Hydroxy-2,2-dimethylpropanoic acid 

Relevant academic research and scientific papers

Design and Synthesis of Novel N-(2-aminophenyl)benzamide Derivatives as Histone Deacetylase Inhibitors and Their Antitumor Activity Study

Histone deacetylases (HDACs) are promising therapeutic targets for cancer therapy because inhibition of HDACs triggers growth arrest or apoptosis of tumor cells. In the present study, a new series of fluorinated N-(2-aminophenyl)benzamide derivatives were synthesized to investigate potential inhibition of HDACs and associated anticancer activity. Among the synthesized derivatives, compound 24a showed potent inhibitory activity of HDACs and higher antitumor efficacy in human cancer cell lines (HCT-116, MCF-7, and A549) compared with SAHA. Moreover, animal studies demonstrated that compound 24a showed potent in vivo antitumor efficacy in an HCT-116 colon cancer xenograft mouse model.

Hepatitis C Virus Inhibitors

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

Hepatitis C Virus Inhibitors

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

ORGANIC COMPOUNDS

The present invention relates to a compound of formula (I) (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.

Organic Compounds

The present invention relates to compounds of formula I and its salts, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.

Pyridylthio-acylanilide herbicides

Novel herbicidally active pyridylthio-acylanilides of the formula STR1 in which R1, R2 and R3, independently of one another, represent hydrogen, halogen, cyano or trifluoromethyl or alkyl, alkoxy and alkylthio having 1 to 4 carbon atoms in each case, R4 represents halogen, methyl or methoxy, n represents a number 0, 1 or 2, z represents the group (Ia) STR2 or the group (Ib) STR3 where X represents oxygen, sulphur, an N--R10 or N--O--R11 group, or X and Rg tpgether represent the STR4 radical, and the other radicals can have various meanings. Intermediates of the formulae STR5 are also new.