64267-12-5Relevant academic research and scientific papers
Coumarin derivatives act as novel inhibitors of human dipeptidyl peptidase III: Combined in vitro and in silico study
?ubari?, Domagoj,Agi?, Dejan,Be?lo, Drago,Kara?i?, Zrinka,Karna?, Maja,Lisjak, Miroslav,Lon?ari?, Melita,Molnar, Maja,Popovi?, Boris M.,Rastija, Vesna,Tomi?, Sanja
, (2021/06/22)
Dipeptidyl peptidase III (DPP III), a zinc-dependent exopeptidase, is a member of the metalloproteinase family M49 with distribution detected in almost all forms of life. Although the physiological role of human DPP III (hDPP III) is not yet fully elucida
Ros inhibitory activity and cytotoxicity evaluation of benzoyl, acetyl, alkyl ester, and sulfonate ester substituted coumarin derivatives
Salar, Uzma,Mohammed Khan, Khalid,Jabeen, Almas,Faheem, Aisha,Naqvi, Farwa,Ahmed, Shakil,Iqbal, Erum,Ali, Farman,Kanwal,Perveen, Shahnaz
, p. 1099 - 1111 (2020/11/09)
Background: A number of non-steroidal anti-inflammatory drugs (NSAIDs) including aspirin, indomethacin, ibuprofen, flufenamic acid, and phenylbutazone are being clinically used to treat inflammatory disorders. These NSAIDs are associated with serious side
A Regioselective Approach to C3-Aroylcoumarins via Cobalt-Catalyzed C(sp 2)-H Activation Carbonylation of Coumarins
Ansari, Samira,Mirzaei, Siyavash,Pashazadeh, Rahim,Rajai-Daryasarei, Saideh,Shabanian, Meisam,Soheilizad, Mehdi
supporting information, p. 3014 - 3020 (2019/07/22)
A new cobalt-catalyzed C-H bond activation of coumarins with aryl halides or pseudohalides and carbon monoxide insertion to give various 3-aroylcoumarin derivatives is described. It is the first time that CO as C1 feedstock is used as the coupling partners in cobalt-catalyzed regioselective coumarin C-H functionalization reactions. Upon activation with manganese powder, the Co catalyzes the C-H bond activation carbonylation reactions of aryl iodides, bromides, and even triflates under mild conditions, providing the regioselective aroylated products in moderate to good yields.
Palladium-Catalyzed Carbonylation of Coumarin C(sp 2)-H Bonds: A New Entry to Arylcoumarin Ketones
Mirzaei, Siyavash,Rajai-Daryasarei, Saideh,Soheilizad, Mehdi,Kabiri, Roya,Ansari, Samira,Shabanian, Meisam,Pashazadeh, Rahim
, p. 1680 - 1688 (2019/03/26)
A facile and efficient palladium-catalyzed carbonylation of coumarins involving two C-C bond formations has been developed. The C-H bond oxidative functionalization proceeds through aroylation with insertion of carbon monoxide to give arylcoumarin ketones
Metal-Free, Regioselective, Dehydrogenative Cross-Coupling between Formamides/Aldehydes and Coumarins by C–H Functionalization
Gupta, Mohit,Kumar, Prashant,Bahadur, Vijay,Kumar, Krishan,Parmar, Virinder S.,Singh, Brajendra K.
supporting information, p. 896 - 900 (2018/02/27)
A highly efficient, single-step, metal-free synthetic approach to the synthesis of coumarin-3-carboxamides has been developed. The protocol employs tert-butyl peroxybenzoate as a radical initiator to achieve the regioselective carboxamidation of coumarins at C-3 in good-to-moderate yields. The established reaction protocol offers a wide substrate scope as it allows the use of both formamides as well as aldehydes as coupling partners with excellent regioselectivity. Furthermore, mechanistic investigations illustrate that the reaction proceeds by a free-radical pathway.
Anti-MRSA (Multidrug resistant Staphylococcus aureus) activity of 3-substituted coumarins
Salar, Uzma,Khan, Khalid Mohammed,Muhammad, Humaira,Fakhri, Muhammed Imran,Sanaullah,Perveen, Shahnaz,Choudhary, Muhammed Iqbal
, p. 353 - 362 (2018/04/20)
Background: Infectious pathogenic bacteria are the key virulence in our daily life. Especially diseases produced by multidrug resistant Staphylococcus aureus (MRSA) still contributing in morbidity and mortality in humans. Discovery of new and safer antibi
A Regioselective Metal-Free Construction of 3-Aroyl Coumarins by Csp2-H Functionalization
Jafarpour, Farnaz,Abbasnia, Masoumeh
, p. 11982 - 11986 (2016/12/09)
A successive metal-free TBHP-mediated regioselective C-H functionalization of coumarins toward expedient synthesis of 3-aroyl coumarins is unveiled. The ongoing method conducted through the reaction of either coumarins or coumarin-3-carboxylic acids with
Iron-catalyzed regioselective direct coupling of aromatic aldehydes with coumarins leading to 3-aroyl coumarins
Yuan, Jin-Wei,Yin, Qiu-Yue,Yang, Liang-Ru,Mai, Wen-Peng,Mao, Pu,Xiao, Yong-Mei,Qu, Ling-Bo
, p. 88258 - 88265 (2015/11/09)
An efficient protocol for iron-catalyzed cross-coupling of coumarins with aromatic aldehydes has been developed. The various 3-aroyl coumarins were selectively afforded in moderate yields. Some notable features of this protocol are high efficiency, wide f
3-KETOCOUMARINES FOR LED PHOTOCURING
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Paragraph 0077-0079, (2015/10/05)
The present invention relates to 3-ketocoumarines which can be used as photoinitiators in LED photocuring and to a process for curing compositions comprising said 3-ketocoumarines.
KETOCOUMARINS AS PHOTOINITIATORS AND PHOTOSENSITIZERS IN INKS
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Page/Page column 16, (2014/02/16)
A series of novel ketocoumarin photoinitiators are disclosed for use in radiation curing.
