643024-90-2

Upstream product

• 33985-40-9 (3aR,4S,6R,6aR)-tetrahydro-6-methoxy-2,2-dimethylfuro-[3,4-d][1,3]dioxole-4-carbaldehyde 
• 536-74-3 phenylacetylene 
• 4099-85-8 ((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 

Downstream Products

• 643024-91-3 Benzoic acid (R)-1-((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-3-phenyl-prop-2-ynyl ester 
• 883860-02-4 Benzoic acid (R)-1-[(2R,3R,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-methoxy-tetrahydro-furan-2-yl]-3-phenyl-prop-2-ynyl ester 
• 883860-03-5 Acetic acid (E)-(R)-1-[(2R,3R,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-methoxy-tetrahydro-furan-2-yl]-3-phenyl-allyl ester 
• 883860-06-8 Acetic acid (2R,3R,3aR,5R,6R,7S,7aS)-3-acetoxy-2-methoxy-5-phenyl-6-phenylselanyl-hexahydro-furo[3,2-b]pyran-7-yl ester 
• 1053642-13-9 Acetic acid (2R,3R,3aS,5R,6R,7S,7aS)-3-hydroxy-2-methoxy-5-phenyl-6-phenylselanyl-hexahydro-furo[3,2-b]pyran-7-yl ester 
• 883860-01-3 Benzoic acid (R)-1-((2S,3S,4R,5R)-3,4-dihydroxy-5-methoxy-tetrahydro-furan-2-yl)-3-phenyl-prop-2-ynyl ester 
• 883860-07-9 Acetic acid (2R,3R,3aR,5S,7R,7aR)-7-acetoxy-2-methoxy-5-phenyl-hexahydro-furo[3,2-b]pyran-3-yl ester 
• 883860-04-6 Acetic acid (E)-(R)-1-((2S,3S,4R,5R)-3,4-dihydroxy-5-methoxy-tetrahydro-furan-2-yl)-3-phenyl-allyl ester 

Relevant academic research and scientific papers

A stereoselective approach to the core structure of the polyoxin and nikkomycin antibiotics

A stereoselective synthesis of the core structure of the polyoxin and nikkomycin antibiotics is described. Notable elements of the synthesis include the use of an IBX-based oxidation protocol in the high-yielding production of ribosyl aldehydes, and the u