64305-14-2

Upstream product

• 33840-74-3 1-(phenylsulfinyl)propan-2-one 
• 1167415-03-3 (R(S))-phenylsulfinylpropan-2-ol 
• 141-78-6 ethyl acetate 
• 108-98-5 thiophenol 
• 930-69-8 sodium thiophenolate 
• 937-56-4 1-phenylsulfanyl-propan-2-ol 
• 5042-53-5 1-(phenylsulfanyl)acetone 
• 66536-74-1 (S)-(+)-(2-hydroxy-1-propyl)-phenyl thioether 
• 66536-73-0 (R)-1-(phenylsulfinyl)-2-propanone 
• 64304-94-5 (S)-1-(phenylsulfinyl)-propan-2-one 

Downstream Products

• 66536-73-0 (R)-1-(phenylsulfinyl)-2-propanone 
• 66536-74-1 (S)-(+)-(2-hydroxy-1-propyl)-phenyl thioether 
• 113317-69-4 (2R,3R)-3-((R)-Benzenesulfinyl)-butan-2-ol 
• 113317-69-4 (2R,3S)-3-((R)-Benzenesulfinyl)-butan-2-ol 
• 118429-64-4 threo-(S_S^*,2S^*)-1-deuterio-1-phenylsulfinyl-2-propanol 
• 118429-64-4 erythro-(S_S^*,2S^*)-1-deuterio-1-phenylsulfinyl-2-propanol 
• 113317-69-4 (2S,3R)-3-((R)-Benzenesulfinyl)-butan-2-ol 
• 113317-69-4 (2S,3S)-3-((R)-Benzenesulfinyl)-butan-2-ol 
• 118429-64-4 erythro-(R_S^*,2S^*)-1-deuterio-1-phenylsulfinyl-2-propanol 
• 118429-64-4 threo-(R_S^*,2S^*)-1-deuterio-1-phenylsulfinyl-2-propanol 
• 118429-63-3 (S_S^*,2S^*)-3-phenylsulfinyl-2,4-tridecanediol 
• 118429-63-3 (R_S^*,2S^*)-3-phenylsulfinyl-2,4-tridecanediol 

Relevant academic research and scientific papers

A chemo-enzymatic synthesis of chiral secondary alcohols bearing sulfur-containing functionality

A facile method for the preparation of chiral secondary alcohols bearing a sulfur-containing functionality using a chemo-enzymatic approach is described, with the aid of baker's yeast and Candida Antarctica lipase B. A complete set of four stereoisomers o

Formation of single diastereomers of β-hydroxy-sulfoxides by biotransformation of β-ketosulfides using Helminthosporium species NRRL 4671

Single biotransformations of 1-(phenylthio)-2-propanone and 1-(p-methoxyphenylthio)-2-propanone by the fungus Helminthosporium species NRRL 4671 resulted in both sulfur oxidation to the sulfoxide and carbonyl reduction to the alcohol. The corresponding (SS,SC)-1-sulfinyl-2-propanols were obtained as single diastereomers following simple crystallization.

Humicola lanuginosa lipase-catalyzed enantioselective resolution of β-hydroxy sulfides: Versatile synthons for enantiopure β-hydroxy sulfoxides

Humicola lanuginosa lipase-catalyzed acylation of β-hydroxy sulfides provides both the (R)- and (S)-enantiomers in high enantiomeric purity. In two cases the resolved hydroxy sulfides were oxidized to give β-hydroxy sulfoxides in >99% e.e. The effect of substituents on enantioselectivity is discussed.

Effect of Intramolecular Chelation on Configurational Interconversion of Sulphur-stabilized Carbanions

Sulphur-stabilized carbanions R1R2-SO undergo configurational interconversion, which is affected by intramolecular chelation and the bulk of R.

Switching of the Direction of Enzyme-Mediated Oxidation and Reduction of Sulfur-Substituted 2-Propanols and 2-Propanones

Incubation of 1-(phenylsulfenyl)-2-propanone with Corynebacterium equi IFO 3730 grown on hexadecane at pH 6.5 afforded the corresponding 1-substituted S propanols. 1-(Phenylsulfinyl)-2-propanone was also reduced by the microorganism, the product being aff

DIASTEREOSELECTIVE α-ALKYLATION OF β-HYDROXY SULFOXIDES AND ITS APPLICATION TO THE SYNTHESIS OF (+)- AND (-)-DISPARLURE

α-Alkylation of the dianions of β-hydroxy sulfoxides proceeds with high 1,2-asymmetric induction to give threo-α-alkyl-β-hydroxy sulfoxides.The utility of the present reaction was demonstrated in the asymmetric synthesis of (+)- and (-)-cis-7,8-epoxy-2-methyloctadecanes (disparlure).

pH DEPENDENT OXIDATION-REDUCTION OF 1-BENZENESULFENYL-2-PROPANONE AND ITS OXIDES BY A MICROORGANISM

Incubation of 1-benzenesulfenyl-2-propanone with Corynebacterium equi IFO 3730 in a weakly acidic medium afforded (S)-1-benzenesulfenyl-2-propanol.On the contrary, when the cultivation was carried out at pH 8 with the same bacterium, only the (S)-alcohol