64374-26-1Relevant articles and documents
Method for preparing 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine from unsaturated turpentine monoterpene
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Paragraph 0040; 0052-0053, (2017/06/02)
The invention discloses a method for preparing 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine from unsaturated turpentine monoterpene. The unsaturated turpentine monoterpene is used as a raw material and takes a reaction with organic nitrile under the catalysis of strong protonic acid; after full reaction, reaction liquid is neutralized into a neutral state; a non-water-soluble organic solvent is added for extraction; an organic layer is collected and is subjected to still standing; 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine crystals are separated out. 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine solid is hydrolyzed in a polyatomic alcohol solution of inorganic strong base to obtain 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine crude products; negative pressure distillation is performed to obtain 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine pure products. The yield of the 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine product obtained by the method is high; the purity is high. Compared with the existing preparation method, the method has the advantages that the unsaturated turpentine monoterpene which has low cost and is easy to obtain is used as the raw material; the process route is simple; the production cost of the 4-amino-alpha, alpha,4-trimethyl-cyclohexanemethanamine can be effectively reduced; in addition, the method also has the advantages of low toxicity, simple operation process and the like.