6439-88-9

Basic information

• Product Name: 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-8-phenyl-
• CAS NO: 6439-88-9
• Molecular Formula: C14H14N4O2
• Molecular Weight: 270.291
• Mol File: 6439-88-9.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-8-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-8-phenyl-(6439-88-9)
• EPA Substance Registry System: 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-8-phenyl-(6439-88-9)

Safety Data

• Hazardous Substances Data: 6439-88-9(Hazardous Substances Data)

Usage

General Description

1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-8-phenyl- is a chemical compound with the molecular formula C14H14N4O2. It is a derivative of the purine nucleobase and belongs to the xanthine family of compounds. This chemical is also known as caffeine and is commonly found in coffee, tea, and energy drinks. Caffeine is a central nervous system stimulant and is widely consumed for its stimulant effects, including heightened alertness and reduced fatigue. It also has diuretic properties and can have effects on mood and appetite. Due to its widespread use, caffeine is one of the most commonly consumed psychoactive substances in the world.

Upstream product

• 2850-37-5 1-methyl-8-phenylxanthine 
• 77-78-1 dimethyl sulfate 
• 961-45-5 1,3-dimethyl-8-phenylxanthine 
• 74-88-4 methyl iodide 
• 4921-49-7 8-chlorocaffeine 
• 98-80-6 phenylboronic acid 
• 10381-82-5 8-bromocaffeine 
• 591-50-4 iodobenzene 
• 58-08-2 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione 
• 108-86-1 bromobenzene 
• 71-43-2 benzene 
• 80-17-1 benzenesufonyl hydrazide 
• 66003-78-9 triphenylsulfonium trifluoromethanesulfonate 
• 6972-27-6 1,3-Dimethyl-6-chlorouracil 

Relevant articles and documents

Pd/Cu-Catalyzed C-H/C-H Cross Coupling of (Hetero)Arenes with Azoles through Arylsulfonium Intermediates

A highly efficient method for the selective formal C-H/C-H cross-coupling of azoles and (hetero)arenes was established through arylsulfonium intermediates under transition-metal catalysis, which produced a variety of 2-(hetero)aryl azoles in good to excellent yields. Advantages of the reaction included mildness, a good functional group tolerance, a wide range of substrates, a high regio- and chemoselectivity, one-pot procedures, and the late-stage functionalization of complex molecules without the use of oxidants, offering a promising strategy for the transition-metal-catalyzed C-H arylation of azoles.

Copper-Catalyzed Intramolecular C-H Amination: A New Entry to Substituted Xanthine Derivatives

Catalytic synthesis of xanthines was achieved in the presence of a copper catalyst. The process involves copper-catalyzed intramolecular C-H amination of benzamidines that possess a uracil moiety and produces variously substituted xanthines generally in good to high yields. This work introduces a new, facile approach to polysubstituted xanthine compounds..

Arylation, Vinylation, and Alkynylation of Electron-Deficient (Hetero)arenes Using Iodonium Salts

Arylation, vinylation, and alkynylation of electron-deficient arenes and heteroarenes have been achieved by chemoselective C-H zincation followed by copper-catalyzed coupling reactions using iodonium salts. This approach offers a direct and general access to a wide scope of (hetero)biaryls as well as alkenylated and alkynylated heteroarenes under mild conditions. It is particularly useful and valuable for the rapid and modular synthesis of diverse (hetero)aryl compounds, as demonstrated in the synthesis of transient receptor potential vanilloid 1 (TRPV1) antagonists and angiotensin II receptor type 1 (AT1 receptor) antagonists.