64450-65-3Relevant articles and documents
Palladium-Catalyzed ortho-Olefination of Phenyl Acetic and Phenyl Propylacetic Esters via C-H Bond Activation
Hu, Jundie,Guan, Mingyu,Han, Jian,Huang, Zhi-Bin,Shi, Da-Qing,Zhao, Yingsheng
, p. 7896 - 7904 (2015/09/01)
A highly regioselective palladium-catalyzed ester-directed ortho-olefination of phenyl acetic and propionic esters with olefins via C-H bond activation has been developed. A wide variety of phenyl acetic and propionic esters were tolerated in this transformation, affording the corresponding olefinated aromatic compounds. The ortho-olefination of heterocyclic acetic and propionic esters also took place smoothly giving the products in good yields, thus proving the potential utility of this protocol in synthetic chemistry.
Reduction of carboxylic acids using esters of benzotriazole as high-reactivity intermediates
Morales-Serna, Jose Antonio,Garcia-Rios, Erendira,Bernal, Jorge,Paleo, Ehecatl,Gavino, Ruben,Cardenas, Jorge
scheme or table, p. 1375 - 1382 (2011/06/19)
Herein, we describe a simple and practical protocol for the reduction of carboxylic acids via the in situ formation of hydroxybenzotriazole esters followed by reaction with sodium borohydride to give the corresponding alcohols. The reaction proceeds with excellent yields in the presence of water. Georg Thieme Verlag Stuttgart - New York.
REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT
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Page/Page column 23, (2009/01/24)
A reagent for organic synthesis with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic synthesis reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process development. With the reagent, research on and development of, e.g., medicines through, e.g., compound library synthesis, etc. can be accelerated. It can hence contribute to technical innovations in the biochemical industry and chemical industry.