64462-58-4Relevant academic research and scientific papers
Organocatalytic enantioselective synthesis of β-amino sulfonic acid derivatives
Bailly, Laetitia,Bischoff, Laurent,Brière, Jean-Fran?ois,Corrot, Emilie,Deau, Emmanuel,Fouache, Clémence,Le Foll, Alexandra,Levacher, Vincent,Marchand, Pierric,Querniard, Florian
, p. 8348 - 8351 (2021/08/25)
An unprecedented enantioselective conjugate addition reaction of sodium bisulfite to various nitrostyrenes occurred upon the influence of a bifunctional amino-thiourea organocatalyst; a strategy that opens a straightforward route to unprotected chiral tau
Enantioselective Addition of Sodium Bisulfite to Nitroalkenes. A Convenient Approach to Chiral Sulfonic Acids
Sheikhi, Ehsan,Rezaei, Narjes,Castilla, Alvaro,Sanz-Marco, Amparo,Vila, Carlos,Mu?oz, M. Carmen,Pedro, José R.,Blay, Gonzalo
supporting information, p. 5284 - 5287 (2021/10/19)
An enantioselective organocatalytic addition of sodium bisulfite to (E)-nitroalkenes has been developed by using a chiral bifunctional organocatalyst. The present methodology provides a variety of chiral β-nitroethanesulfonic acid compounds (17 examples)
Facile synthesis of various substituted taurines, especially syn- and anti-1,2-disubstituted taurines, from nitroolefins
Chen, Ning,Xu, Jiaxi
, p. 2513 - 2522 (2012/04/11)
Taurine and substituted taurines present a group of important structural elements in many natural products. Various substituted taurines, including 1- and 2-substituted, 1,1-, syn-1,2-, and anti-1,2-disubstituted taurines, were synthesized from the corresponding nitroolefins via Michael addition with thioacetic acid, oxidation with peroxyformic acid, and the catalytic hydrogenation under the catalysis of palladium on carbon or platinum dioxide. It is a general, versatile, and salt-free method for the preparation of substituted taurines, especially for syn- and anti-1,2-disubstituted taurines and some taurines with more bulky substituents. The stereostructures of both syn- and anti-1,2-disubstituted taurines were deduced from the nitroalkyl thioacetates in the Michael addition, which were identified via the Karplus equation analysis and computational analysis, and finally confirmed by the XRD single crystal analysis. The diastereoselectivity in the Michael addition was rationalized with the Cram rule.
Versatile synthesis of α-substituted taurines from nitroolefins
Xu, Chuanxiang,Xu, Jiaxi
experimental part, p. 195 - 203 (2012/04/10)
A series of 1-substituted and 1,1-disubstituted taurines were synthesized from nitroolefins via the Michael addition with sodium ethylxanthate, oxidation with performic acid, and reduction with hydrogen in the presence of palladium on carbon powder. The current route is a versatile and salt-free method for synthesis of both aliphatic and aromatic 1-substituted and 1,1-disubstituted taurines. Springer-Verlag 2010.
A METHOD FOR PREPARING SULFUR-CONTAINING COMPOUNDS
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Page/Page column 13-15, (2010/06/22)
The invention provides a method for preparing sulfur-containing compounds, the method comprising reacting a donor compound comprising at least one sulfur having at least one lone pair of electrons, with an acceptor compound; wherein the reaction occurs in
Development of a mild procedure for the addition of bisulfite to electrophilic olefins
Fini, Francesco,Nagabelli, Murali,Adamo, Mauro F. A.
supporting information; experimental part, p. 3163 - 3168 (2011/02/22)
The sulfonylation of activated alkenes is an important yet unexplored reaction due to the harshness of conditions required. We have identified a procedure which allowed the reaction of alkenes with equimolar amounts of bisulfite at room temperature. Copyr
