29651-81-8Relevant academic research and scientific papers
Organocatalytic enantioselective Michael addition of thioacetic acid to enones
Li, Hao,Zu, Liansuo,Wang, Jian,Wang, Wei
, p. 3145 - 3148 (2006)
An enantioselective, organocatalytic Michael addition reaction of thioacetic acid with enones has been developed. The process, catalyzed by a chiral bifunctional amine thiourea, furnishes products in excellent yields with up to 63% ee.
Enantio- and diastereoselective addition of thioacetic acid to nitroalkenes via N-sulfinyl urea catalysis
Kimmel, Kyle L.,Robak, Maryann T.,Thomas, Stephen,Lee, Melissa,Ellman, Jonathan A.
experimental part, p. 2704 - 2712 (2012/04/17)
The enantioselective addition of thioacetic acid to nitroalkenes was achieved using N-sulfinyl urea catalysis. In this report, the scope of the reaction was extended to the enantio- and diastereoselective thioacetic acid addition to cyclic α,β-disubstitut
Enantioselective addition of thioacetic acid to nitroalkenes via N-sulfinyl urea organocatalysis
Kimmel, Kyle L.,Robak, MaryAnn T.,Ellman, Jonathan A.
supporting information; experimental part, p. 8754 - 8755 (2009/12/04)
(Chemical Equation Presented) The highly enantioselective addition of thioacetic acid to nitroalkenes using a new sulfinyl urea organocatalyst is described. The addition of thioacetic acid proceeds in high yields and enantioselectivities for a variety of
