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tert-butyl 3-(trifluoromethyl)pyrrolidine-1-carboxylate is a chemical compound with the molecular formula C9H14F3NO2. It is a derivative of pyrrolidine-1-carboxylate, featuring a trifluoromethyl group at the 3-position and a tert-butyl group at the 1-position. tert-butyl 3-(trifluoromethyl)pyrrolidine-1-carboxylate is known for its potential applications in medicinal chemistry and drug development.

644970-40-1

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644970-40-1 Usage

Uses

Used in Pharmaceutical Industry:
tert-butyl 3-(trifluoromethyl)pyrrolidine-1-carboxylate is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable building block in the development of new drugs targeting chemokine receptors.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, tert-butyl 3-(trifluoromethyl)pyrrolidine-1-carboxylate serves as a key component in the design and synthesis of novel compounds with potential therapeutic applications. Its ability to modulate chemokine receptors makes it a promising candidate for the treatment of disorders affected by these receptors.
Used in Drug Development for Chemokine Receptor Modulation:
tert-butyl 3-(trifluoromethyl)pyrrolidine-1-carboxylate is used as a modulator of chemokine receptors for the development of drugs targeting disorders affected by the modulation of these receptors. Its involvement in the regulation of immune responses and inflammation makes it a potential therapeutic agent for conditions such as autoimmune diseases, inflammatory disorders, and cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 644970-40-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,4,9,7 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 644970-40:
(8*6)+(7*4)+(6*4)+(5*9)+(4*7)+(3*0)+(2*4)+(1*0)=181
181 % 10 = 1
So 644970-40-1 is a valid CAS Registry Number.

644970-40-1Relevant academic research and scientific papers

Synthesis of trifluoromethyl-substituted 3-azabicyclo[n.1.0]alkanes: Advanced building blocks for drug discovery

Artamonov, Olexiy S.,Slobodyanyuk, Evgeniy Y.,Volochnyuk, Dmitriy M.,Komarov, Igor V.,Tolmachev, Andrey A.,Mykhailiuk, Pavel K.

, p. 3592 - 3599 (2014/06/23)

Five CF3-substituted 3-azabicyclo[n.1.0]alkanes were synthesized by CuCl-mediated trifluoromethylcyclopropanation reaction of the corresponding cyclic enamides with CF3CHN2. Copyright

NOVEL TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES

-

, (2008/06/13)

The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, R3, R4, R5, R6, R7, R8, t and R9 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

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