6451-85-0

Upstream product

• 100-44-7 benzyl chloride 
• 81038-45-1 2-bromo-5-hydroxy-4-methoxyphenyl-acetonitrile 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 

Downstream Products

• 13425-04-2 5-benzyloxy-4-methoxy-2-bromophenylacetic acid 
• 13232-98-9 N-(4'-benzyloxy-2-bromo-4-methoxyphenyl)-N-(4'-benzyloxy-3'-methoxyphenylethyl)acetamide 
• 227088-17-7 7-benzyloxy-1-(5'-benzyloxy-2'-bromo-4'-methoxybenzyl)-6-methoxy-3,4-dihydroisoquinoline 
• 892804-24-9 2,10-di(benzyloxy)-3,9-dimethoxy-5,6-dihydroindolo[2,1-a]isoquinoline 
• 892804-31-8 2,10-di(benzyloxy)-3,9-dimethoxy-5,6,12,12a-tetrahydroindolo[2,1-a]isoquinoline 
• 892805-32-2 N-(4'-benzyloxy-3'-methoxyphenylethyl)-2-(2-bromo-5-hydroxy-4-methoxyphenyl)acetamide 

Relevant academic research and scientific papers

The palladium-catalyzed preparation of condensed tetracyclic heterocycles and their application to the synthesis of rac-mangochinine

Dihydroisoquinoline derivatives and their analogues, prepared by the Bischler-Napieralsky reaction, were converted to their indole-fused derivatives. Scope and limitations of the palladium-catalyzed reaction, proceeding through the tautomeric enamine forms of these compounds, were studied and the process was extended to the preparation of racemic mangochinine. Georg Thieme Verlag Stuttgart.