81038-45-1Relevant academic research and scientific papers
Stereoselective synthesis of tetrahydroisoquinoline alkaloids: (-)-trolline, (+)-crispin A, (+)-oleracein e
Kawai, Nobuyuki,Matsuda, Mika,Uenishi, Jun'Ichi
experimental part, p. 8648 - 8653 (2011/12/01)
Tetrahydroisoquinoline alkaloids, (S)-(-)-trolline, (R)-(+)-crispin A, and (R)-(+)-oleracein E, have been synthesized stereoselectively from the both enantiomers of common intermediate (S)-4 and (R)-4. The key step in the synthesis include a stereoselecti
The palladium-catalyzed preparation of condensed tetracyclic heterocycles and their application to the synthesis of rac-mangochinine
Vincze, Zoltan,Biro, A. Beatrix,Csekei, Marton,Timari, Geza,Kotschy, Andras
, p. 1375 - 1385 (2007/10/03)
Dihydroisoquinoline derivatives and their analogues, prepared by the Bischler-Napieralsky reaction, were converted to their indole-fused derivatives. Scope and limitations of the palladium-catalyzed reaction, proceeding through the tautomeric enamine forms of these compounds, were studied and the process was extended to the preparation of racemic mangochinine. Georg Thieme Verlag Stuttgart.
