645394-70-3

Upstream product

• 645394-66-7 N-((1S,2S)-3-(tert-Butyl-dimethyl-silanyloxy)-1-{(4S,5S)-5-[(2E,4E)-5-(4-ethoxy-phenyl)-penta-2,4-dienyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-methoxymethoxy-propyl)-2,2,2-trifluoro-acetamide 
• 645394-65-6 N-((1S,2S)-3-(tert-Butyl-dimethyl-silanyloxy)-1-{(4S,5S)-5-[(2E,4E)-5-(4-ethoxy-phenyl)-penta-2,4-dienyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-hydroxy-propyl)-2,2,2-trifluoro-acetamide 
• 645394-67-8 N-((1S,2S)-1-{(4S,5S)-5-[(2E,4E)-5-(4-Ethoxy-phenyl)-penta-2,4-dienyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-3-hydroxy-2-methoxymethoxy-propyl)-2,2,2-trifluoro-acetamide 
• 645394-63-4 N-((S)-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-{(4S,5S)-5-[(2E,4E)-5-(4-ethoxy-phenyl)-penta-2,4-dienyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methyl)-2,2,2-trifluoro-acetamide 
• 645394-64-5 N-((1S,2S)-1-{(4S,5S)-5-[(2E,4E)-5-(4-Ethoxy-phenyl)-penta-2,4-dienyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2,3-dihydroxy-propyl)-2,2,2-trifluoro-acetamide 
• 645394-61-2 N-[(S)-[(4S,5S)-5-(2-Benzenesulfonyl-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-2,2,2-trifluoro-acetamide 
• 645394-58-7 Methanesulfonic acid (R)-[(4R,5S)-5-(2-benzenesulfonyl-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl ester 
• 645394-59-8 (4S,5S)-4-[(S)-Azido-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-5-(2-benzenesulfonyl-ethyl)-2,2-dimethyl-[1,3]dioxolane 
• 645394-60-1 C-[(S)-C-[(4S,5S)-5-(2-Benzenesulfonyl-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-C-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)]-methylamine 
• 645394-56-5 (S)-3-Benzenesulfonyl-1-((4R,5R,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-propan-1-ol 
• 645394-57-6 (R)-[(4S,5S)-5-(2-Benzenesulfonyl-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol 
• 645394-53-2 4-azido-3-(tert-butyl-dimethyl-silanyloxy)-butyric acid methyl ester 
• 38145-93-6 (S)-1-((4R,4'R,5R)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)ethane-1,2-diol 
• 90-80-2 D-Glucono-1,5-lactone 

Downstream Products

• 206535-31-1 microsclerodermin E 
• 645394-71-4 (2S,3R)-3-[(R)-4-Azido-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-3-{(4S,5S)-5-[(2E,4E)-5-(4-ethoxy-phenyl)-penta-2,4-dienyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-methoxymethoxy-propionic acid 
• 645394-72-5 (2S,3R)-3-[(R)-4-Azido-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-3-{(4S,5S)-5-[(2E,4E)-5-(4-ethoxy-phenyl)-penta-2,4-dienyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-methoxymethoxy-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 645394-89-4 C₅₁H₆₄N₈O₁₅ 

Relevant academic research and scientific papers

Total Synthesis of Microsclerodermin E

Succumbing to total synthesis: Microsclerodermin E, a 23-membered cyclic hexapeptide possessing antifungal activity, has been prepared for the first time. Key features in the synthesis include the construction of four unusual amino acid units, the assembl