645403-03-8Relevant academic research and scientific papers
Enantiodivergent synthesis of cytotoxic styryl lactones from d-xylose. The first total synthesis of (+)- and (-)-crassalactone C
Popsavin, Velimir,Benedekovi?, Goran,Sre?o, Bojana,Francuz, Jovana,Popsavin, Mirjana,Koji?, Vesna,Bogdanovi?, Gordana,Divjakovi?, Vladimir
experimental part, p. 10596 - 10607 (2010/03/03)
Enantiodivergent total syntheses of both (+)- and (-)-enantiomers of goniofufurone, 7-epi-goniofufurone and crassalactone C have been accomplished starting from d-xylose. The key steps of the synthesis of 7-epi-(+)-goniofufurone were a stereo-selective ad
Synthesis and antiproliferative activity of unnatural enantiomers of 7-epi-goniofufurone and crassalactone C
Popsavin, Velimir,Benedekovic, Goran,Sreco, Bojana,Popsavin, Mirjana,Francuz, Jovana,Kojic, Vesna,Bogdanovic, Gordana
scheme or table, p. 5178 - 5181 (2009/05/07)
A facile synthesis of 7-epi-(-)-goniofufurone as well as the first synthesis of (-)-crassalactone C was achieved starting from d-xylose. A comparison of their in vitro antitumour activities with those observed for the corresponding naturally occurring enantiomers was provided.
