15354-75-3Relevant academic research and scientific papers
Enantiodivergent synthesis of cytotoxic styryl lactones from d-xylose. The first total synthesis of (+)- and (-)-crassalactone C
Popsavin, Velimir,Benedekovi?, Goran,Sre?o, Bojana,Francuz, Jovana,Popsavin, Mirjana,Koji?, Vesna,Bogdanovi?, Gordana,Divjakovi?, Vladimir
experimental part, p. 10596 - 10607 (2010/03/03)
Enantiodivergent total syntheses of both (+)- and (-)-enantiomers of goniofufurone, 7-epi-goniofufurone and crassalactone C have been accomplished starting from d-xylose. The key steps of the synthesis of 7-epi-(+)-goniofufurone were a stereo-selective ad
Synthesis and antiproliferative activity of unnatural enantiomers of 7-epi-goniofufurone and crassalactone C
Popsavin, Velimir,Benedekovic, Goran,Sreco, Bojana,Popsavin, Mirjana,Francuz, Jovana,Kojic, Vesna,Bogdanovic, Gordana
scheme or table, p. 5178 - 5181 (2009/05/07)
A facile synthesis of 7-epi-(-)-goniofufurone as well as the first synthesis of (-)-crassalactone C was achieved starting from d-xylose. A comparison of their in vitro antitumour activities with those observed for the corresponding naturally occurring enantiomers was provided.
Enantiodivergent synthesis of muricatacin related lactones from d-xylose based on the latent symmetry concept: preparation of two?novel cytotoxic (+)- and (-)-muricatacin 7-oxa analogs
Popsavin, Velimir,Krsti?, Ivana,Popsavin, Mirjana,Sre?o, Bojana,Benedekovi?, Goran,Koji?, Vesna,Bogdanovi?, Gordana
, p. 11044 - 11053 (2007/10/03)
Enantiodivergent formal synthesis of (+)- and (-)-muricatacins from d-xylose has been accomplished through utilization of the?latent plane of symmetry present in the starting monosaccharide. This approach was extended to the preparation of two novel (+)-
[3+2] Cycloaddition reactions: A simple entry to the 1-aza-2-oxo-3,4,5,6- tetrahydroxybicyclo[3.3.0]octane ring system
Roy, Ashim,Roy, Biswajit G.,Achari, Basudeb,Mandal, Sukhendu B.
, p. 5811 - 5814 (2007/10/03)
The [3+2] intramolecular nitrone cycloaddition (INC) reaction on appropriately designed olefinic nitrones derived from D-glucose, having the nitrone at C-1 and α,β-unsaturated ester functionalities at C-5 of the sugar backbone, afforded the isoxazolidine
Enantiopure hydroxylactones from D-xylose. A novel approach to the enantiodivergent synthesis of (+)- and (-)-muricatacin suitable for the preparation of 7-oxa analogues
Popsavin, Velimir,Krsti?, Ivana,Popsavin, Mirjana
, p. 8897 - 8900 (2007/10/03)
A new route towards enantiopure hydroxylactones 3 and ent-3, the final chiral precursors in an enantiodivergent synthesis of (+)- and (-)-muricatacin, has been developed starting from D-xylose.
