645403-07-2Relevant academic research and scientific papers
Enantiodivergent synthesis of muricatacin related lactones from d-xylose based on the latent symmetry concept: preparation of two?novel cytotoxic (+)- and (-)-muricatacin 7-oxa analogs
Popsavin, Velimir,Krsti?, Ivana,Popsavin, Mirjana,Sre?o, Bojana,Benedekovi?, Goran,Koji?, Vesna,Bogdanovi?, Gordana
, p. 11044 - 11053 (2007/10/03)
Enantiodivergent formal synthesis of (+)- and (-)-muricatacins from d-xylose has been accomplished through utilization of the?latent plane of symmetry present in the starting monosaccharide. This approach was extended to the preparation of two novel (+)-
Synthesis and?antitumour activity of?new muricatacin and?goniofufurone analogues
Popsavin, Velimir,Sre?o, Bojana,Krsti?, Ivana,Popsavin, Mirjana,Koji?, Vesna,Bogdanovi?, Gordana
, p. 1217 - 1222 (2007/10/03)
A divergent approach to the 7-oxa (-)-muricatacin analogue 2, the corresponding (+)-enantiomer ent-2 and the furanolactone 3 is reported starting from d-xylose. The resulting lactones have shown a potent and selective in vitro cytotoxicity against certain
Enantiopure hydroxylactones from D-xylose. A novel approach to the enantiodivergent synthesis of (+)- and (-)-muricatacin suitable for the preparation of 7-oxa analogues
Popsavin, Velimir,Krsti?, Ivana,Popsavin, Mirjana
, p. 8897 - 8900 (2007/10/03)
A new route towards enantiopure hydroxylactones 3 and ent-3, the final chiral precursors in an enantiodivergent synthesis of (+)- and (-)-muricatacin, has been developed starting from D-xylose.
