646066-95-7Relevant academic research and scientific papers
A ratiometric fluorescent sensor for Ag1 with high selectivity and sensitivity
Yang, Rong-Hua,Chan, Wing-Hong,Lee, Albert W. M.,Xia, Ping-Fang,Zhang, Hong-Kui,Li, Ke'An
, p. 2884 - 2885 (2003)
A bicyclic cycloadduct 1 bearing a pyrenyl moiety has been synthesized and investigated as a ratiometric fluorescent sensor for AgI. In an aqueous ethanol solution of 1, the presence of silver ion induces the formation of a 1:2 metal-ligand complex, which exhibits a strong intensity enhancement of the pyrene excimer emission at the expense of the emission of monomeric pyrene. Copyright
Synthesis and tyrosinase inhibitory activity of novel N-hydroxybenzyl-N-nitrosohydroxylamines
Shiino, Mitsuhiro,Watanabe, Yumi,Umezawa, Kazuo
, p. 129 - 135 (2007/10/03)
Several novel N-substituted N-nitrosohydroxylamines were synthesized. They all inhibited mushroom tyrosinase, but the type of inhibition was different depending on the substituent. Some N-(mono- or dihydroxybenzyl)-N-nitrosohydroxylamines exhibited uncompetitive inhibition with respect to L-dopa. Among them, compound 6 was also a competitive inhibitor with respect to oxygen. This observation suggests that another interaction by the meta- or para-hydroxyl group might stabilize the binding of the inhibitor to the enzyme through the oxygen binding site.
