6461-07-0

Basic information

• Product Name: L-Phenylalanine, L-leucyl-, methyl ester, monohydrochloride
• CAS NO: 6461-07-0
• Molecular Formula: C16H24N2O3.ClH
• Molecular Weight: 328.839
• Mol File: 6461-07-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, L-leucyl-, methyl ester, monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, L-leucyl-, methyl ester, monohydrochloride(6461-07-0)
• EPA Substance Registry System: L-Phenylalanine, L-leucyl-, methyl ester, monohydrochloride(6461-07-0)

Safety Data

• Hazardous Substances Data: 6461-07-0(Hazardous Substances Data)

Usage

General Description

L-Phenylalanine, L-leucyl-, methyl ester, monohydrochloride is a chemical compound that is a derivative of the amino acids phenylalanine and leucine. It is commonly used in the field of biochemistry and pharmaceuticals for various research and development purposes. L-Phenylalanine, L-leucyl-, methyl ester, monohydrochloride is a monohydrochloride salt, which means it is a salt containing one equivalent of hydrochloric acid and one equivalent of the amino acid derivative. It is known to have potential applications in the synthesis of peptide and protein-based drugs, as well as in the development of new therapeutic treatments for various diseases and medical conditions. This chemical compound is also of interest in the study of cellular processes and can be used in the creation of new drug delivery systems.

Upstream product

• 188783-08-6 N-[N-(2-benzoyl-2-ethoxycarbonylvinyl-1)-L-leucyl]-L-3-phenylalanine methyl ester 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 66866-44-2 Boc-Leu-O-COO-isoBu 
• 61-90-5 L-leucine 
• 63-91-2 L-phenylalanine 

Downstream Products

• 876953-59-2 (S)-2-[(S)-1-((S)-1-Methoxycarbonyl-2-phenyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1338587-03-3 (S)-tert-butyl 3-(((S)-1-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1365292-35-8 L-isoseryl-L-leucyl-L-phenylalanine methyl ester hydrochloride 
• 868539-96-2 (S)-methyl 2-((S)-2-tert.butoxycarbonyIamino-4-phenylbutanamido-4-methylpentanamido)-3-phenylpropanoate 
• 868540-17-4 carfilzomib 
• 868540-16-3 (S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenyipropanoic acid 
• 1140908-89-9 C₃₂H₄₄N₄O₆ 
• 1410924-85-4 methyl N-acetyl-(S)-prolyl-(S)-leucyl-(S)-phenylalaninate 
• 108456-25-3 methyl (2S,5S)-2-benzyl-8-[(tert-butoxycarbonyl)amino]-5-isobutyl-4,7-dioxo-3,6-diazaoctanoate 
• 1414357-46-2 methyl (S)-2-{(S)-2-[2-((S)-2-{4-[(8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6Hcyclopenta[a]phenanthren-17-yl]-1H-1,2,3-triazol-1-yl}propanamido)acetamido]-4-methylpentanamido}-3-phenylpropanoate 
• 1414357-91-7 methyl (S)-2-((S)-2-{2-[(S)-2-azidopropanamido]acetamido}-4-methylpentanamido)-3-phenylpropanoate 
• 1374225-27-0 C₅₅H₉₃N₉O₁₂ 
• 3354-31-2 (3S,6S)-3-benzyl-6-isobutylpiperazine-2,5-dione 
• 1367281-41-1 C₁₈H₂₅BrN₂O₄ 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF (2S)-N-((S)-1-((S)-4-METHYL-1-((R)-2-METHYL OXIRAN-2-YL)-1-OXOPENTAN-2-YLCARBAMOYL)-2-PHENYLETHYL)-2-((S)-2-(2-MORPHOLINO ACETAMIDO)-4-PHENYLBUTANAMIDO)-4-METHYLPENTANAMIDE

The present invention relates to process for the preparation of (2S)-N-((S)-l -((S)-4-methyl-1 -((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylcarbamoyl)-2-phenylethyl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)-4 -methylpentanamide represented by the following structural formula-1.

Influence of neighboring groups on the thermodynamics of hydrophobic binding: An added complex facet to the hydrophobic effect

The thermodynamic consequences of systematic modifications in a ligand side chain that binds in a shallow hydrophobic pocket, in the presence and absence of a neighboring ligand carboxylate group, were evaluated using isothermal titration calorimetry (ITC

Cyclic dipeptides exhibit potency for scavenging radicals

Twenty kinds of cyclic dipeptides containing l-leucine were synthesized, and their antioxidant activity against .OH and O2·- was investigated. Compounds possessing polar amino acid residues, such as Asp, Cys, Glu, Lys, Pro, Ser, and Trp, exhibited higher antioxidant activity against .OH than vitamin E. However, only cyclo(l-Cys-l-Leu) scavenged O2·-.