876953-56-9

Basic information

• Product Name: L-Phenylalanine, (4R)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester
• CAS NO: 876953-56-9
• Molecular Formula: C27H41N3O6S
• Molecular Weight: 535.705
• Mol File: 876953-56-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, (4R)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, (4R)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester(876953-56-9)
• EPA Substance Registry System: L-Phenylalanine, (4R)-1-[(1,1-dimethylethoxy)carbonyl]-4-(methylthio)-L-prolyl-L-leucyl-, methyl ester(876953-56-9)

Safety Data

• Hazardous Substances Data: 876953-56-9(Hazardous Substances Data)

Upstream product

• 121147-93-1 (2S,4S)-2-methyl N-Boc-4-((methylsulfonyl)oxy)pyrrolidine-2-carboxylate 
• 87691-27-8 N-tert-butoxycarbonyl-L-cis-4-hydroxyproline 
• 84348-37-8 N-tert-butoxycarbonyl-4-oxo-L-proline 
• 15136-32-0 (N-(tert-butoxycarbonyl)-L-leucinyl)-L-phenylalanine methyl ester 
• 188111-18-4 1-(tert-butyl) 2-methyl (2S,4R)-4-(acetylthio)pyrrolidine-1,2-dicarboxylate 
• 876953-58-1 N-(tert-butyloxycarbonyl)-trans-4-(methylthio)-L-proline 
• 6461-07-0 methyl (S)-2-[(S)-2-amino-4-methylpentanamido]-3-phenylpropanoate hydrochloride 
• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 
• 74844-91-0 (2S,4S)-N-tert-butoxycarbonyl-4-hydroxyproline methyl ester 

Relevant articles and documents

Chemotactic peptides: fMLF-OMe analogues incorporating proline-methionine chimeras as N-terminal residue

The new fMLF analogues 1-4, incorporating chimeric S-proline-methionine residues (namely the homochiral cis-4(S)-methylthio-(S)-proline (10) and the heterochiral trans-4(R)-methylthio-(S)-proline) (17) in place of the native S-methionine, have been prepared; their solution conformation and activity as agonists or antagonists of formylpeptide receptors have been studied. In addition to peptides 1-4, which maintain the Met γ-thiomethyl-ether function, the analogues Boc-PLF-OMe (18) and For-PLF-OMe (19) devoid, as compared with 1-4, of position 1 side chain, have been synthesized and their activity examined.