6468-96-8Relevant articles and documents
Dual Role of Oxoaldehydes: Divergent Synthesis of 3-Aryl- and 3-Aroylcoumarins
Moazzam, Ali,Khodadadi, Meysam,Jafarpour, Farnaz,Ghandi, Mehdi
, p. 3630 - 3637 (2022/02/16)
A facile and efficient synthetic approach to various valuable 3-aryl- and 3-aroylcoumarins by the direct arylation and aroylation of coumarins with glyoxals in a metal-free manner is presented. The aryl glyoxal is for the first time recognized to serve as an aryl surrogate in addition to its role as an aroyl transfer reagent via a simple switch in reaction conditions. The approach accommodates a broad substrate scope and high yields of the two types of cross-coupling reactions starting from identical starting materials.
Chlorophyll-catalyzed photochemical regioselective coumarin C-H arylation with diazonium salts
Moazzam, Ali,Jafarpour, Farnaz
supporting information, p. 16692 - 16696 (2020/10/27)
This communication describes the development of a mild method for the cross-coupling of the C3-position of coumarin with an array of diazonium salts mediated by chlorophyll as a biocatalyst via visible light catalysis. A natural pigment such as chlorophyll is used as a green photosensitizer and environmentally benign catalyst. This general and easy procedure provides a transition-metal-free alternative for the formation of 3-aryl coumarin derivatives at room temperature with good to excellent yields. This journal is
3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease
Abdshahzadeh, Helia,Golshani, Mostafa,Nadri, Hamid,Saberi Kia, Iraj,Abdolahi, Zahra,Forootanfar, Hamid,Ameri, Alieh,Tüylü Kü?ükk?l?n?, Tuba,Ayazgok, Beyza,Jalili-Baleh, Leili,Sadat Ebrahimi, Seyed Esmaeil,Moghimi, Setareh,Haririan, Ismaeil,Khoobi, Mehdi,Foroumadi, Alireza
, (2019/04/17)
Two series of novel coumarin derivatives, substituted at 3 and 7 positions with aminoalkoxy groups, are synthesized, characterized, and screened. The effect of amine substituents and the length of cross-linker are investigated in acetyl- and butyrylcholin