647025-83-0Relevant academic research and scientific papers
Oligocyclization of 2-(hydroxymethyl)pyrroles with electron-withdrawing groups at β-positions: Formation and structural elucidation of porphyrinogens and hexaphyrinogens
Uno, Hidemitsu,Inoue, Kentarou,Inoue, Takashi,Ono, Noboru
, p. 3857 - 3865 (2007/10/03)
Acid-catalyzed oligomerization of 2-(hydroxymethyl)pyrroles bearing C6F5, 2,6-Cl2C6H3, CF3 and CO2Et groups at β-positions was examined. The reaction of ethyl pyrrole-3-carboxylates gave a mixture of oligomers and type I isomers of porphyrinogens and hexaphyrinogens were isolated when the other β-substituents were sufficiently bulky, for example, mesityl, 2,6-Cl2C6H3 and C6F5 groups. On the other hand, the pyrroles having other electron-withdrawing groups afforded porphyrinogens as the only isolable products.
