64773-74-6Relevant academic research and scientific papers
Synthesis of new heterocycles festooned with thiophene and evaluating their antioxidant activity
Abed, Nader A.,Hammouda, Mohamed M.,Ismail, Mohamed A.,Abdel-Latif, Ehab
, p. 4153 - 4163 (2020/09/09)
The chemical performance of 5-bromo-2-(bromoacetyl)-thiophene (1) was tested toward the reaction with numerous bi-nucleophilic reagents (namely; 2-aminobenzothiazoles, 2-aminothiazole, 2-aminotetrazole, 2-aminotriazole, 2-aminopyridines, 2-aminobenzimidaz
A novel synthesis of spiro 1,3-dithiin and spiro 1,3-thiazine derivatives under Phase Transfer Catalysis (PTC) conditions
El-Saghier, Ahmed M. M.
, p. 1237 - 1250 (2007/10/03)
Ketene S,S-acetals 1a,b or ketene N,S-acetals 2a,b reacts in situ with a variety of ylidenemalononitriles to afford the desired spiro [1,3]dithiin heterocycles 3a,b-11a,b or spiro[1,3/thiazine heterocycles 12a,b-20a,b. Treatment of 2-(1-acetyl-2-oxopropyl
Heterocyclic Synthesis With Isothiocyanates: An Expeditious Synthetic Route to Polyfunctionally Substituted Thiophene, Pyrazole, Oxazole, 2,3-Dihydrothiazole, 2-(Pyrazol-4-ylidene)thiazole and 5-(thiazol-2-ylidene)pyrimidine Derivatives
El-Kousy, Sallah M.,Mohareb, Rafat M.,Sherif, Sherif M.
, p. 1981 - 1996 (2007/10/02)
The acidic methylene reagents 1a-e react with phenyl isothiocyanate followed by reaction with bromomalononitrile to afford acyclic and cyclic products 3,4,8,9 and 14a-c depending on the nature of the active methylene reagent used.The reactivions of the products towards different chemical reagents to afford thiophene, pyrazole, oxazole and pyrimidine derivatives were studied.
