647851-99-8Relevant academic research and scientific papers
Double chirality transmission in trityl amines: Sensing molecular dynamic stereochemistry by circular dichroism and DFT calculations
Sciebura, Jacek,Gawronski, Jacek
experimental part, p. 13138 - 13141 (2012/02/02)
Con-figured out: The tert-butyl group can be formally seen as "less" sterically demanding (M) than the methyl group (L). This is the case when a CD-active trityl group at the nitrogen atom is used to report the chirality of the carbon substituent with two
A practical diastereoselective synthesis of β-amino-α-hydroxy carboxylates
Lee, Jae-Mok,Lim, Hyun-Suk,Seo, Kyung-Chang,Chung, Sung-Kee
, p. 3639 - 3641 (2007/10/03)
Practical synthetic routes to β-amino-α-hydroxy carboxylates (AHC) have been developed from amino acids. Reduction of β-amino-α- keto esters 6 with NaBH4 was found to give anti-AHCs 7 in high de, which were efficiently converted to the corresponding syn-AHCs 8 via oxazolidine ring 10 formation.
