6479-17-0

Basic information

• Product Name: 2-Quinoxalinamine, N-methyl-
• Synonyms: 2-Quinoxalinamine, N-methyl-
• CAS NO: 6479-17-0
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.19
• Mol File: 6479-17-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 306.6°C at 760 mmHg
• Flash Point: 139.2°C
• Appearance: /
• Density: 1.229g/cm³
• Vapor Pressure: 0.000765mmHg at 25°C
• Refractive Index: 1.697
• CAS DataBase Reference: 2-Quinoxalinamine, N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Quinoxalinamine, N-methyl-(6479-17-0)
• EPA Substance Registry System: 2-Quinoxalinamine, N-methyl-(6479-17-0)

Safety Data

• Hazardous Substances Data: 6479-17-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H9N3/c1-10-9-6-11-7-4-2-3-5-8(7)12-9/h2-6H,1H3,(H,10,12)

Upstream product

• 106-96-7 propargyl bromide 
• 90537-58-9 N-methyl-3-chloroquinoxaline-2-amine 
• 108-95-2 phenol 
• 13610-02-1 1-phenoxy-2-propyne 
• 95-54-5 1,2-diamino-benzene 
• 1196-57-2 quinoxalin-2⁽¹⁾-one 
• 1448-87-9 2-chloroquinoxaline 
• 74-89-5 methylamine 

Relevant articles and documents

Novel one-pot synthesis of 1-alkyl-2-(aryloxy)methyl-1H-pyrrolo[2,3-b]quinoxalines via copper-free Sonogashira coupling reaction

Abstract: A novel, simple, and efficient protocol is described for the synthesis of 1-alkyl-2-(aryloxy)methyl-1H-pyrrolo[2,3-b]quinoxalines via the one-pot reaction of phenol or 2-naphthol derivatives, propargyl bromide, and N-alkyl-3-chloroquinoxaline-2-amines in the presence of palladium catalyst. This one-pot reaction is carried out in the absence of any copper salt at room temperature. The reaction product is dependent on the nature of the base used. The use of morpholine, as the base, affords the final cyclized product, and triethylamine only gives the coupling product. Graphical abstract: [Figure not available: see fulltext.].