64798-50-1Relevant articles and documents
Facile synthesis of the glucosylceramide synthase inhibitor GZ667161
Hewlett, Elizabeth D.,Melenski, Edward,Qiu, Frederick V.,Leung, Hiu T.,Jacobson, Marlene,Qiu, Feng,Abou-Gharbia, Magid,Childers, Wayne
, (2020/09/10)
GZ667161 (GZ-161) is a quinuclidine-based small molecule inhibitor of the lysosomal enzyme glucosylceramide synthase. It represents an important tool molecule for studying the contribution of glycosphingolipids to disease pathology in lysosomal storage di