64805-62-5

Basic information

• Product Name: D-(S)-3-acetylthio-2-methylpropionylL-proline
• Synonyms: 1-(3-(ACETYLTHIO)-2-METHYLPROPIONYL)-L-PROLINE;1-(3-Acetylthio)-2-methyl-1-oxopropyl)-L-proline;L-Proline,1-[3-(acetylthio)-2-Methyl-1-oxopropyl]-
• CAS NO: 64805-62-5
• Molecular Formula: C₁₁H₁₇NO₄S
• Molecular Weight: 259.32198
• Mol File: 64805-62-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: D-(S)-3-acetylthio-2-methylpropionylL-proline(CAS DataBase Reference)
• NIST Chemistry Reference: D-(S)-3-acetylthio-2-methylpropionylL-proline(64805-62-5)
• EPA Substance Registry System: D-(S)-3-acetylthio-2-methylpropionylL-proline(64805-62-5)

Safety Data

• Hazardous Substances Data: 64805-62-5(Hazardous Substances Data)

Usage

General Description

D-(S)-3-acetylthio-2-methylpropionyl-L-proline is a chemical compound that belongs to the class of proline derivatives. It is a chiral molecule, with a specific stereochemistry known as (S). D-(S)-3-acetylthio-2-methylpropionylL-proline is used in pharmaceutical and biochemical research due to its potential biological activities. It has been studied for its potential antiviral, anti-inflammatory, and antioxidant properties. Additionally, it has been investigated for its potential use in the treatment of various diseases and conditions. Its unique structure and potential medicinal properties make it a valuable compound for further research and development.

Upstream product

• 33325-40-5 3-(acetylthio)-2-methylpropanoic acid 
• 64805-64-7 3-(Acetylthio)-2-methylpropionyl chloride 
• 147-85-3 L-proline 
• 76497-39-7 (2S)-3-acetylthio-2-methylpropionic acid 
• 51161-88-7 N-methacryloyl-L-proline 
• 507-09-5 tiolacetic acid 

Relevant articles and documents

Tetrahydroisoquinoline derivative and application thereof

The invention belongs to the technical field of medicines, relates to a 2-{(2s)-1-[(2S)-3-ethanethioate-2-methyl propionyl] pyrrolidine-2-formamido}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester derivative and an application thereof, and in particular relates to a stereomer and a pharmaceutically acceptable salt of the compound. The general structural formula is as shown in the specification. The 2-{(2s)-1-[(2S)-3-ethanethioate-2-methyl propionyl] pyrrolidine-2-formamido}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester compound as well as pharmaceutically acceptable acid and additive salt of the compound can be combined with an existing medicine and can be individually used as an angiotensin-converting enzyme inhibitor to be applied to treatment of hypertension. Compared with the prior art, 6,7,8 side chains of a tetrahydroisoquinoline ring are obviously changed; the inhibition rate of the sample on angiotensin-converting enzyme is significantly improved; and the tetrahydroisoquinoline derivative has good application values and development and application prospects.

Process for preparing an angiotensin converting enzyme inhibitor

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Azetidine-2-carboxylic acid derivatives

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