6482-32-2

Basic information

• Product Name: 2-(hydroxyMethyl)butane-1,4-diol
• Synonyms: 2-(hydroxyMethyl)butane-1,4-diol;2-(HydroxyMethyl)-1,4-butanediol
• CAS NO: 6482-32-2
• Molecular Formula: C₅H₁₂O₃
• Molecular Weight: 120.14698
• Mol File: 6482-32-2.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 331.3 °C at 760 mmHg
• Flash Point: 154.1 °C
• Appearance: /
• Density: 1.22 g/cm³
• PKA: 14.37±0.10(Predicted)
• CAS DataBase Reference: 2-(hydroxyMethyl)butane-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(hydroxyMethyl)butane-1,4-diol(6482-32-2)
• EPA Substance Registry System: 2-(hydroxyMethyl)butane-1,4-diol(6482-32-2)

Safety Data

• Hazardous Substances Data: 6482-32-2(Hazardous Substances Data)

Usage

General Description

2-(hydroxymethyl)butane-1,4-diol, also known as D-mannitol or mannitol, is a sugar alcohol derived from glucose. It is a white, crystalline powder with a sweet taste and is commonly used as a sweetening agent in various food and beverage products. Mannitol has also been used as a medication to reduce pressure inside the eyes, to treat certain kidney conditions, and as a diuretic to increase urine production. Additionally, mannitol is used as an excipient in pharmaceutical formulations to improve the stability and shelf life of medications. Overall, 2-(hydroxymethyl)butane-1,4-diol has a wide range of applications in the food, pharmaceutical, and medical industries due to its sweetening properties and various therapeutic benefits.

Upstream product

• 7459-46-3 triethyl 1,1,2-ethanetricarboxylate 
• 94853-87-9 2-carboxy-oxiranylacetic acid 
• 97-65-4 2-methylenesuccinic acid 
• 5472-38-8 diethyl 2-formylbutanedioate 
• 58026-12-3 dimethyl formylsuccinate 
• 63972-17-8 1,3-diethyl 2-(2-hydroxyethyl)propanedioate 

Downstream Products

• 115430-92-7 5-(2-hydroxyethyl)-1,3-dioxane 
• 119880-87-4 2-(Bromomethyl)-1,4-dibromobutane 
• 949891-55-8 C₈H₁₆O₃ 
• 102147-75-1 2,2-dimethyl-5-(2'-hydroxyethyl)-1,3-dioxane 
• 124391-75-9 3-tetrahydrofuranmethanol 
• 1296137-06-8 (E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(1-(4-hydroxy-3-(hydroxymethyl)butyl)-1H-indol-3-yl)acrylamide 
• 1296137-05-7 (E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(1-(4-hydroxy-3-(hydroxymethyl)butyl)-1H-imidazol-4-yl)acrylamide 
• 1296137-04-6 (E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(1-(4-hydroxy-3-(hydroxymethyl)butyl)-1H-pyrazol-4-yl)acrylamide 
• 1296137-03-5 (E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(1-(4-hydroxy-3-(hydroxymethyl)butyl)-1H-pyrrol-2-yl)acrylamide 
• 119880-85-2 2,7,16-Trithia<3^5,11><8>metacyclophane 

Relevant articles and documents

NANOMATERIALS

Lipid nanoparticle compositions for delivery of nucleic acids are described. In various embodiments the lipid nanoparticle contains an ionizable lipid of the Formula (I). Methods of using such lipid nanoparticle compositions to achieve targeted delivery of therapeutic cargo without the need for a targeting ligand are also provided.

FLAME RETARDANT ITACONIC ACID-BASED COMPOUNDS

A flame retardant itaconic acid-based compound, a process for forming a flame retardant polymer, and an article of manufacture comprising a material that contains a flame retardant itaconic acid-based polymer are disclosed. The flame retardant itaconic acid-based compound has variable moieties, which include methylene bridge groups, carbonyl groups, vinyl groups, functionalized groups, phenyl-substituted flame retardant groups, and/or functionalized flame retardant groups. The process for forming the flame retardant polymer includes forming a phosphorus-based flame retardant molecule, forming an itaconic acid derivative, chemically reacting the phosphorus-based flame retardant molecule and the itaconic acid derivative to form a flame retardant itaconic acid-based compound, and incorporating the itaconic acid-based flame retardant compound into a polymer to form the flame retardant polymer.

Method for synthesizing 3-tetrahydrofurfuryl alcohol

The invention relates to a method for synthesizing 3-tetrahydrofurfuryl alcohol. According to the technical scheme, 2-bromoethanol and diethyl malonate serve as starting materials, under the alkaline condition, 2-hydroxyethyl-diethyl malonate is generated through a reaction, hydrolysis is conducted on the 2-hydroxyethyl-diethyl malonate to generate 2-hydroxyethyl-malonate, catalyzing and high-pressure hydrotreatment are conducted on the 2-hydroxyethyl-malonate to generate 2-hydroxymethyl-1,4-butanediol, and dehydration cyclization is conducted on the 2-hydroxyethyl-1,4-butanediol to generate the 3-tetrahydrofurfuryl alcohol. According to the method for synthesizing the 3-tetrahydrofurfuryl alcohol, the yield can reach over 85 percent, the purity can reach above 95 percent, the reaction condition is mild, the cost is low, operation is easy, and the method has the advantage of being suitable for industrial production.