64826-30-8Relevant academic research and scientific papers
Synthesis of phenols and aryl silyl ethers via arylation of complementary hydroxide surrogates
Reitti, Marcus,Gurubrahamam, Ramani,Walther, Melanie,Lindstedt, Erik,Olofsson, Berit
, p. 1785 - 1788 (2018/04/14)
Two transition-metal-free methods to access substituted phenols via the arylation of silanols or hydrogen peroxide with diaryliodonium salts are presented. The complementary reactivity of the two nucleophiles allows synthesis of a broad range of phenols without competing aryne formation, as illustrated by the synthesis of the anesthetic Propofol. Furthermore, silyl-protected phenols can easily be obtained, which are suitable for further transformations.
COPPER(I) IODIDE ASSISTED REACTION OF NONACTIVATED IODOARENES WITH SODIUM TRIFLUOROACETATE IN HEXAMETHYLPHOSPHORIC TRIAMIDE. NUCLEAR TRIFLUOROMETHYLATION AND DIARYL ETHER FORMATION
Suzuki, Hitomi,Yoshida, Yoshiki,Osuka, Atsuhiro
, p. 135 - 136 (2007/10/02)
Polymethyliodobenzenes react with sodium trifluoroacetate, in the presence of copper(I) iodide, in hexamethylphosphoric triamide at 150-180 deg C, giving a mixture of the corresponding polymethylbenzotrifluoride, parent hydrocarbon, and bis(polymethylphenyl) ether.
