64834-27-1Relevant academic research and scientific papers
Lariat-bearing cyclophosphazenes: potential molecular sepulchers for magnetic resonance imaging agents
Valerio, Christine,Labarre, Marie-Christine,Labarre, Jean-Francois
, p. 171 - 176 (1993)
Lariat-bearing cyclophosphazenes were prepared by aminolysis of hexachlorocyclotriphosphazene with amino ester hydrochlorides followed by standard alkaline hydrolysis.These cryptands are actually capable complexing gadolinium cations with stability constants larger than 1E28; this is much larger than the values for classical magnetic resonance imaging agents.Unfortunately, these cryptates are much too insoluble in physiological serum to be used for clinical purposes in a facile way.
