
Journal of Molecular Structure p. 171 - 176 (1993)
Update date:2022-08-02
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Valerio, Christine
Labarre, Marie-Christine
Labarre, Jean-Francois
Lariat-bearing cyclophosphazenes were prepared by aminolysis of hexachlorocyclotriphosphazene with amino ester hydrochlorides followed by standard alkaline hydrolysis.These cryptands are actually capable complexing gadolinium cations with stability constants larger than 1E28; this is much larger than the values for classical magnetic resonance imaging agents.Unfortunately, these cryptates are much too insoluble in physiological serum to be used for clinical purposes in a facile way.
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