648411-35-2 Usage
Uses
Used in Pharmaceutical Drug Development:
1H-Thieno[3,2-c]pyrazole-5-carboxylic acid, 3-amino-, methyl ester is utilized as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique chemical structure allows for the creation of novel drug candidates with potential therapeutic benefits.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1H-Thieno[3,2-c]pyrazole-5-carboxylic acid, 3-amino-, methyl ester serves as a valuable tool for studying the structure-activity relationships of drug molecules. It aids researchers in understanding the molecular mechanisms underlying drug action and optimizing drug design for improved efficacy and safety.
Used in Drug Discovery:
1H-Thieno[3,2-c]pyrazole-5-carboxylic acid, 3-amino-, methyl ester is employed in high-throughput screening assays to identify potential drug candidates with desired biological activities. Its presence in compound libraries facilitates the rapid identification of promising leads for further optimization and development.
Used in Biochemical Studies:
1H-Thieno[3,2-c]pyrazole-5-carboxylic acid, 3-amino-, methyl ester is also used in biochemical studies to investigate its interactions with various biological targets, such as enzymes, receptors, and other proteins. Understanding these interactions can provide insights into the molecular basis of diseases and guide the development of targeted therapies.
Overall, 1H-Thieno[3,2-c]pyrazole-5-carboxylic acid, 3-amino-, methyl ester is a versatile chemical compound with significant applications across various domains of pharmaceutical and medicinal chemistry, making it an essential component in the pursuit of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 648411-35-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,8,4,1 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 648411-35:
(8*6)+(7*4)+(6*8)+(5*4)+(4*1)+(3*1)+(2*3)+(1*5)=162
162 % 10 = 2
So 648411-35-2 is a valid CAS Registry Number.
648411-35-2Relevant academic research and scientific papers
Thieno[3,2-c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity
Bindi, Simona,Fancelli, Daniele,Alli, Cristina,Berta, Daniela,Bertrand, Jay A.,Cameron, Alexander D.,Cappella, Paolo,Carpinelli, Patrizia,Cervi, Giovanni,Croci, Valter,D'Anello, Matteo,Forte, Barbara,Laura Giorgini,Marsiglio, Aurelio,Moll, Juergen,Pesenti, Enrico,Pittalà, Valeria,Pulici, Maurizio,Riccardi-Sirtori, Federico,Roletto, Fulvia,Soncini, Chiara,Storici, Paola,Varasi, Mario,Volpi, Daniele,Zugnoni, Paola,Vianello, Paola
experimental part, p. 7113 - 7120 (2010/10/21)
A novel series of 3-amino-1H-thieno[3,2-c]pyrazole derivatives demonstrating high potency in inhibiting Aurora kinases was developed. Here we describe the synthesis and a preliminary structure-activity relationship, which led to the discovery of a represe
Heterobicyclic pyrazole derivatives as kinase inhibitors
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Page/Page column 15, (2008/06/13)
Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in
HETEROBICYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS
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Page 60-61, (2010/02/06)
Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in
