648411-40-9Relevant articles and documents
Thieno[3,2-c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity
Bindi, Simona,Fancelli, Daniele,Alli, Cristina,Berta, Daniela,Bertrand, Jay A.,Cameron, Alexander D.,Cappella, Paolo,Carpinelli, Patrizia,Cervi, Giovanni,Croci, Valter,D'Anello, Matteo,Forte, Barbara,Laura Giorgini,Marsiglio, Aurelio,Moll, Juergen,Pesenti, Enrico,Pittalà, Valeria,Pulici, Maurizio,Riccardi-Sirtori, Federico,Roletto, Fulvia,Soncini, Chiara,Storici, Paola,Varasi, Mario,Volpi, Daniele,Zugnoni, Paola,Vianello, Paola
experimental part, p. 7113 - 7120 (2010/10/21)
A novel series of 3-amino-1H-thieno[3,2-c]pyrazole derivatives demonstrating high potency in inhibiting Aurora kinases was developed. Here we describe the synthesis and a preliminary structure-activity relationship, which led to the discovery of a represe
Heterobicyclic pyrazole derivatives as kinase inhibitors
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Page/Page column 16, (2008/06/13)
Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in
HETEROBICYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS
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Page 41-42, (2010/02/06)
Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in
