648434-01-9

Upstream product

• 209173-80-8 2(RS)-hydroxy-3(S)-amino-4-phenylbutanoic acid 
• 100-52-7 benzaldehyde 
• 191849-93-1 3(S)-(N-tert-butoxycarbonylamino)-2(R,S)-hydroxy-4-phenylbutyric acid 
• 209174-37-8 3(S)-amino-2(R,S)-hydroxy-4-phenylbutyric acid methyl ester 
• 648433-99-2 3(S)-(N-Cbz-leucylamino)-2(R,S)-hydroxy-4-phenylbutanoic acid hydrazide 
• 261786-25-8 3(S)-(N-Cbz-leucylamino)-2(R,S)-hydroxy-4-phenylbutanoic acid methyl ester 

Downstream Products

• 648434-03-1 N'N'-(benzyl)(tert-butyloxycarbonylamino)-3(S)-(N-Cbz-leucylamino)-4-phenyl-2-oxobutanoic acid hydrazide 
• 648434-02-0 N'N'-(benzyl)(tert-butyloxycarbonylamino)-3(S)-(N-Cbz-leucylamino)-2(R,S)-hydroxy-4-phenylbutanoic acid hydrazide 

Relevant academic research and scientific papers

Design, Synthesis, Molecular Modeling Studies, and Calpain Inhibitory Activity of Novel α-Ketoamides Incorporating Polar Residues at the P 1′-Position

A series of novel α-ketoamides incorporating stereoisomeric residues with different electronic properties at the P1′-position were synthesized to study the electronic requirements for inhibitor binding to the S1′-subsite of calpain I