64854-00-8Relevant academic research and scientific papers
Asymmetric approach toward chiral cyclohex-2-enones from anisoles via an enantioselective isomerization by a new chiral diamine catalyst
Lee, Jung Hwa,Deng, Li
, p. 18209 - 18212 (2012)
A 3-step asymmetric approach toward the optically active chiral cyclohex-2-enones from anisoles has been developed. The crucial asymmetric induction step is an unprecedented catalytic enantioselective isomerization of β,γ-unsaturated cyclohex-3-en-1-ones
Total Syntheses of Crinipellins Enabled by Cobalt-Mediated and Palladium-Catalyzed Intramolecular Pauson–Khand Reactions
Huang, Zhihui,Huang, Jun,Qu, Yongzheng,Zhang, Weibin,Gong, Jianxian,Yang, Zhen
supporting information, p. 8744 - 8748 (2018/07/14)
Efficient total syntheses of the naturally occurring, potent antibiotic compounds (?)-crinipellin A and (?)-crinipellin B are described. The key advanced intermediate, a fully functionalized tetraquinane core, was constructed by a novel thiourea/palladium-catalyzed Pauson–Khand reaction. This intermediate can serve as a common intermediate for the collective total synthesis of other members of the crinipellin family.
