6487-38-3

Basic information

• Product Name: 3-Hydroxypropionic acid sodium salt
• Synonyms: 3-Hydroxypropionic acid sodium salt;3-Hydroxypropanoic Acid MonosodiuM Salt;3-Hydroxypropanoic Acid SodiuM Salt;Hydracrylic Acid SodiuM Salt;SodiuM β-Hydroxypropionate;Propanoic acid, 3-hydroxy-, sodium salt (1:1);Sodium 3-hydroxypropanoate
• CAS NO: 6487-38-3
• Molecular Formula: C₃H₅O₃*Na
• Molecular Weight: 0
• Product Categories: Aliphatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 6487-38-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: DMSO (Slightly, Heated), Water (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 3-Hydroxypropionic acid sodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxypropionic acid sodium salt(6487-38-3)
• EPA Substance Registry System: 3-Hydroxypropionic acid sodium salt(6487-38-3)

Safety Data

• Hazardous Substances Data: 6487-38-3(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis Industry:
3-Hydroxypropionic acid sodium salt is used as a building block for the synthesis of various compounds, such as acrylic acid, acrylamide, and 1,3-propanediol, which have a wide range of applications in different industries.
Used in Biodegradable Polymer Production:
3-Hydroxypropionic acid sodium salt is used in the preparation of acrylates and biodegradable polymer polyester, contributing to the development of environmentally friendly materials.
Used in Medical Diagnostics:
3-Hydroxypropionic acid sodium salt serves as a biomarker for detecting defects in propionic acid and branched-chain amino acid catabolism in patients with methylmalonic acidemia or propionic acidemia, aiding in the diagnosis and treatment of these conditions.

Upstream product

• 106087-08-5 3-amino-1-methyl-1-phenyl-4,5-dihydropyrazol-1-ium iodide 
• 106087-10-9 3-Amino-1-phenyl-1-propyl-4,5-dihydro-1H-pyrazol-1-ium; iodide 
• 75-21-8 oxirane 
• 50-00-0 formaldehyd 
• 106087-11-0 3-Amino-1-isopropyl-1-phenyl-4,5-dihydro-1H-pyrazol-1-ium; iodide 
• 106087-12-1 3-Amino-1-butyl-1-phenyl-4,5-dihydro-1H-pyrazol-1-ium; iodide 
• 106087-09-6 3-amino-1-ethyl-4,5-dihydro-1-phenyl-1H-pyrazolium iodide 
• 84533-99-3 3-amino-4,5-dihydro-1,4-dimethyl-1-phenyl-1H-pyrazolium iodide 
• 6439-49-2 1-(2-carbamylethyl)-1,1-dimethylhydrazinium chloride 

Downstream Products

• 7446-81-3 sodium 2-propenoate 

Relevant articles and documents

PURIFICATION OF 1,3-PROPANEDIOL BY DISTILLATION

The present invention is a process for purification of 1,3-propanediol (PDO) by an inverted distillation sequence which comprises: (a) optionally removing water or other solvents from the crude 1,3-propanediol mixture; (b) distilling the crude 1,3-propanediol mixture under conditions which maximize the separation of components of the mixture which are heavier than 1,3-propanediol from the 1,3-propanediol and the components which are lighter than 1,3-propanediol; (c) drawing off a stream which contains at least most of the 1,3-propanediol and at least some of the components of the mixture which are lighter than 1,3-propanediol; and (d) distilling the stream of (c) to separate the 1,3-propanediol from components in the stream which are lighter than 1,3-propanediol and any residual components which are heavier than 1,3-propanediol.

Amidrazones. 14. The Formation of 1,1-Disubstituted Hydrazines from the Base-promoted Hydrolysis of 1,1-Disubstituted-3-amino-4,5-dihydro-1H-pyrazolium Halides: Mechanistic Considerations

Three mechanistic pathways are considered for the hydroxide-promoted conversion of 1,1-disubstituted-3-amino-4,5-dihydro-1H-pyrazolium halides 1 to 1,1-disubstituted hydrazines, ammonia and sodium 3-hydroxypropanoate.Evidence presented in this paper supports a hydrolysis mechanism c that is initiated by hydroxide ion addition to the 3-position of 1 to form a tetrahedral intermediate 7.

AMIDRAZONES 9. CONVENIENT SYNTHESIS OF 1-ALKYL-1-PHENYLHYDRAZINES AND α,β-UNSATURATED AMIDRAZONES VIA BASE-PROMOTED REACTIONS OF 1,1-DISUBSTITUTED-3-AMNIO-4,5-DIHYDRO-1H-PYRAZOLIUM SALTS.

A simple, efficient procedure for the conversion of phenylhydrazine to 1-alkyl-1-phenylhydrazines via base-promoted hydrolysis of 1-alkyl-3-amino-4,5-dihydro-1-phenyl-1H-pyrazolium iodides (2) is described.N',N'-disubstituted hydrazones of trans-cinnamamide and acrylamide are obtained by Hofmann-type ring openings of 1,1-disubstituted-3-amino-4,5-dihydro-5-phenyl (or 5-unsubstituted) -1H-pyrazolium halides (5,7).