64875-04-3 Usage
Uses
Used in Pharmaceutical Industry:
D-Alanine, N-(2,2,3,3,3-pentafluoro-1-oxopropyl)-, 1-methylethyl ester is used as a building block in the synthesis of peptides and pharmaceuticals. Its unique chemical properties allow it to be incorporated into the structure of various drugs, potentially enhancing their efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, D-Alanine, N-(2,2,3,3,3-pentafluoro-1-oxopropyl)-, 1-methylethyl ester is utilized in the development of new agrochemicals. Its incorporation into the molecular structure of these compounds can lead to improved performance and selectivity in agricultural applications.
Used in Research Applications:
D-Alanine, N-(2,2,3,3,3-pentafluoro-1-oxopropyl)-, 1-methylethyl ester is also used in various research applications. Its unique chemical properties make it a valuable tool for studying peptide synthesis, protein structure, and the development of new drugs and materials.
Used as a Protecting Group in Peptide Synthesis:
The 1-methylethyl ester group in D-Alanine, N-(2,2,3,3,3-pentafluoro-1-oxopropyl)-, 1-methylethyl ester makes it a useful protecting group for amino acids during peptide synthesis. This feature allows for the controlled formation of peptide bonds and the synthesis of complex peptide structures with greater precision and efficiency.
Check Digit Verification of cas no
The CAS Registry Mumber 64875-04-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,8,7 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 64875-04:
(7*6)+(6*4)+(5*8)+(4*7)+(3*5)+(2*0)+(1*4)=153
153 % 10 = 3
So 64875-04-3 is a valid CAS Registry Number.
64875-04-3Relevant academic research and scientific papers
Champacyclin, a new cyclic octapeptide from Streptomyces strain C42 isolated from the Baltic Sea
Pesic, Alexander,Baumann, Heike I.,Kleinschmidt, Katrin,Ensle, Paul,Wiese, Jutta,Suessmuth, Roderich D.,Imhoff, Johannes F.
, p. 4834 - 4857 (2014/02/14)
New isolates of Streptomyces champavatii were isolated from marine sediments of the Gotland Deep (Baltic Sea), from the Urania Basin (Eastern Mediterranean), and from the Kiel Bight (Baltic Sea). The isolates produced several oligopeptidic secondary metabolites, including the new octapeptide champacyclin (1a) present in all three strains. Herein, we report on the isolation, structure elucidation and determination of the absolute stereochemistry of this isoleucine/leucine (Ile/Leu = Xle) rich cyclic octapeptide champacyclin (1a). As 2D nuclear magnetic resonance (NMR) spectroscopy could not fully resolve the structure of (1a), additional information on sequence and configuration of stereocenters were obtained by a combination of multi stage mass spectrometry (MSn) studies, amino acid analysis, partial hydrolysis and subsequent enantiomer analytics with gas chromatography positive chmical ionization/electron impact mass spectrometry (GC-PCI/EI-MS) supported by comparison to reference dipeptides. Proof of the head-to-tail cyclization of (1a) was accomplished by solid phase peptide synthesis (SPPS) compared to an alternatively side chain cyclized derivative (2). Champacyclin (1a) is likely synthesized by a non-ribosomal peptide synthetase (NRPS), because of high content of (D)-amino acids. The compound (1a) showed antimicrobial activity against the phytopathogen Erwinia amylovora causing the fire blight disease of certain plants.
