6488-88-6

Basic information

• Product Name: 1H-Benzimidazole,2-(1H-pyrazol-1-yl)-(9CI)
• Synonyms: 1H-Benzimidazole,2-(1H-pyrazol-1-yl)-(9CI);1H-BenziMidazole,2-(1H-pyrazol-1-yl);2-(1H-Pyrazol-1-yl)-1H-1,3-benzodiazole
• CAS NO: 6488-88-6
• Molecular Formula: C10H8N4
• Molecular Weight: 184.19732
• Product Categories: BENZIMIDAZOLE
• Mol File: 6488-88-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 220-221 °C
• Boiling Point: 427.7±28.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• PKA: 10.61±0.10(Predicted)
• CAS DataBase Reference: 1H-Benzimidazole,2-(1H-pyrazol-1-yl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,2-(1H-pyrazol-1-yl)-(9CI)(6488-88-6)
• EPA Substance Registry System: 1H-Benzimidazole,2-(1H-pyrazol-1-yl)-(9CI)(6488-88-6)

Safety Data

• Hazardous Substances Data: 6488-88-6(Hazardous Substances Data)

Usage

General Description

"1H-Benzimidazole, 2-(1H-pyrazol-1-yl)-(9CI)" is a chemical compound with the molecular formula C10H8N4. It contains a benzimidazole ring and a pyrazole ring, which are both aromatic heterocycles. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. 1H-Benzimidazole,2-(1H-pyrazol-1-yl)-(9CI) has been studied for its potential biological activities, including antimicrobial, antifungal, and anti-inflammatory properties. It is important to handle this chemical with care, as it may have potential hazards if not used properly.

Upstream product

• 930-36-9 1-methyl-1H-pyrazole 
• 4857-06-1 2-chloro-1H-benzoimidazole 
• 15108-18-6 2-hydrazinobenzimidazole 
• 102-52-3 malonaldehydebis(dimethylacetal) 
• 288-13-1 NH-pyrazole 
• 615-16-7 1,3-dihydro-2H-benzimidazol-2-one 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 95-54-5 1,2-diamino-benzene 
• 134469-07-1 Benzimidazol-2-thiol 
• 133797-82-7 1-(1H-benzimidazol-2-yl)-2-methyl-pyrazolium chloride 

Downstream Products

• 6488-97-7 1-methyl-2-(1-pyrazolyl)benzimidazole 

Relevant articles and documents

Metallosupramolecular architectures based upon new 2-(1-pyrazolyl)-benzimidazole chelating ligands

In this article, we report the synthesis and characterisation of five ligands L1-L5 containing the 2-(pyrazol-1-yl)-benzimidazole chelating group, and investigate their structural chemistry when reacted with either Cu(II) or Zn(II) ions. The mononuclear c

Direct, metal-free amination of heterocyclic amides/ureas with NH-heterocycles and N-substituted anilines in POCl3

A POCl3-mediated, direct amination reaction of heterocyclic amides/ureas with NH-heterocycles or N-substituted anilines is described. Compared to the existing methods, this operationally simple protocol provides unique reactivity and functional

Reaction of 2-hydrazinobenzimidazole with β-diketones: A structural reinvestigation

The reaction of 2-hydrazinobenzimidazole (1) with pentane-2,4-dione yields a pyrazole derivative (2) instead of the reported triazepine (3).Several 2-pyrazolylbenzimidazoles (4) have similarly been synthesized using unsymmetrical β-diketones and their precursors.It has been shown that 1H NMR spectroscopy can easily distinguish the isomeric pairs.